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10.3345/cep.2020.01795

http://scihub22266oqcxt.onion/10.3345/cep.2020.01795
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33539697!8024123!33539697
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suck abstract from ncbi


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pmid33539697      Clin+Exp+Pediatr 2021 ; 64 (4): 157-164
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  • Clinical implications of coronavirus disease 2019 in neonates #MMPMID33539697
  • Kim DH
  • Clin Exp Pediatr 2021[Apr]; 64 (4): 157-164 PMID33539697show ga
  • Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019, a small number of coronavirus disease 2019 (COVID-19) cases in neonates have been reported worldwide. Neonates currently account for only a minor proportion of the pediatric population affected by COVID-19. Thus, data on the epidemiological and clinical features of COVID-19 in neonates are limited. Approximately 3% of neonates born to mothers with COVID-19 reportedly tested positive for SARS-CoV-2. Current limited data on neonates with COVID-19 suggest that neonatal COVID-19 shows a relatively benign course despite a high requirement for mechanical ventilation. However, neonates with pre-existing medical conditions and preterm infants appear to be at a higher risk of developing severe COVID-19. The greatest perinatal concern of the COVID-19 pandemic is the possibility of vertical transmission, especially transplacental transmission of SARS-CoV-2. Although direct evidence of the vertical transmission of SARS-CoV-2 is lacking, its possibility during late pregnancy cannot be ruled out. This review summarizes available case studies on COVID-19 in neonates and introduces what is currently known about neonatal COVID-19 with focus on its vertical transmission.
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