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10.1080/1744666X.2021.1886080 http://scihub22266oqcxt.onion/10.1080/1744666X.2021.1886080 33538189!ä!33538189 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Expert+Rev+Clin+Immunol 2021 ; 17 (3): 201-208 Nephropedia Template TP {{tp|p=33538189|t=2021. Dangerous liaisons? The role of inflammation and comorbidities in HIV and SARS-CoV-2 infection |pdf=|usr=}}{{33538189}} gab.com Text Dangerous liaisons The role of inflammation and comorbidities in HIV and SARS-CoV-2 infection JO: Expert Rev Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=33538189 #FOAvip INTRODUCTION: In people living with HIV (PLWH), immune activation and inflammation levels are high even when viral suppression is maintained, potentially contributing to several comorbidities, and hampering the immune response to infections such as the recent SARS-CoV-2 disease 2019 (COVID-19). AREAS COVERED: Immune activation and inflammation play a role in SARS-CoV-2 infection. Severe COVID-19 patients may experience cytokine release syndrome (CRS), leading to alveolar damage, pulmonary fibrinolysis, dysregulated coagulation, and pulmonary injury. Into the systemic circulation, cytokines in excess might leak out of pulmonary circulation, causing systemic symptoms and possibly a multiple-organ dysfunction syndrome. Preexisting comorbidities are also linked to worse COVID-19 outcome: studies suggest that diabetes and hypertension are linked to higher mortality rates. Such comorbidities are more frequent in PLWH, but it is unclear if they have worse outcomes in the case of COVID-19. The literature was searched in PubMed/MEDLINE and EMBASE, and manually in COVID-19 resources. EXPERT OPINION: A body of evidence shows that HIV and SARS-CoV-2 are able to activate inflammatory pathways, acute in the case of SARS-CoV-2, chronic in the case of HIV, while the comorbidities seem to represent, in the first case, a contributory cause, in the second an effect of the virus-induced damage. Twit Text FOAVip Dangerous liaisons The role of inflammation and comorbidities in HIV and SARS-CoV-2 infection ????Expert Rev Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=33538189 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33538189 #FOAvip English Wikipedia <ref>{{Cite pmid|33538189}}</ref> Dangerous liaisons? The role of inflammation and comorbidities in HIV and SARS-CoV-2 infection #MMPMID33538189 Maggi P; Ricci E; Messina V; Salzillo A; Simeone F; Iodice A; Socio GV Expert Rev Clin Immunol 2021[Mar]; 17 (3): 201-208 PMID33538189show ga INTRODUCTION: In people living with HIV (PLWH), immune activation and inflammation levels are high even when viral suppression is maintained, potentially contributing to several comorbidities, and hampering the immune response to infections such as the recent SARS-CoV-2 disease 2019 (COVID-19). AREAS COVERED: Immune activation and inflammation play a role in SARS-CoV-2 infection. Severe COVID-19 patients may experience cytokine release syndrome (CRS), leading to alveolar damage, pulmonary fibrinolysis, dysregulated coagulation, and pulmonary injury. Into the systemic circulation, cytokines in excess might leak out of pulmonary circulation, causing systemic symptoms and possibly a multiple-organ dysfunction syndrome. Preexisting comorbidities are also linked to worse COVID-19 outcome: studies suggest that diabetes and hypertension are linked to higher mortality rates. Such comorbidities are more frequent in PLWH, but it is unclear if they have worse outcomes in the case of COVID-19. The literature was searched in PubMed/MEDLINE and EMBASE, and manually in COVID-19 resources. EXPERT OPINION: A body of evidence shows that HIV and SARS-CoV-2 are able to activate inflammatory pathways, acute in the case of SARS-CoV-2, chronic in the case of HIV, while the comorbidities seem to represent, in the first case, a contributory cause, in the second an effect of the virus-induced damage. |Blood Coagulation Disorders/epidemiology/immunology[MESH] |COVID-19/*epidemiology/*immunology[MESH] |Comorbidity[MESH] |Cytokines/immunology[MESH] |Diabetes Mellitus/epidemiology/immunology[MESH] |HIV Infections/*epidemiology/*immunology[MESH] |Humans[MESH] |Hyperglycemia/epidemiology/immunology[MESH] |Hypertension/epidemiology/immunology[MESH] |Inflammation[MESH] |Metabolic Syndrome/epidemiology/immunology[MESH]Dangerous liaisons? The role of inflammation and comorbidities in HIV (epmc).pdf DeepDyve Pubget Overpricing