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Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Neurol 2021 ; 268 (9): 3125-3128 Nephropedia Template TP
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Complement inhibition initiated recovery of a severe myasthenic crisis with COVID-19 #MMPMID33537898
Hofstadt-van Oy U; Stankovic S; Kelbel C; Oswald D; Larrosa-Lombardi S; Barchfeld T; Cleff U
J Neurol 2021[Sep]; 268 (9): 3125-3128 PMID33537898show ga
We report on a patient with refractory Myasthenia gravis with acetylcholine receptor antibodies with two prior myasthenic crises suffering from COVID-19 with rapid evolving weakness and respiratory failure. Respiratory failure developed and prolonged mechanical ventilation was necessary. After plasmapheresis, residual, severe generalized and bulbar weakness persisted. Complement inhibition with eculizumab was, therefore, introduced and lead to rapid recovery. In refractory myasthenic crisis individualised therapies could be successful.