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10.3389/fmolb.2020.616798 http://scihub22266oqcxt.onion/10.3389/fmolb.2020.616798 33537341!7847895!33537341     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33537341&cmd=llinks): Failed to open stream: HTTP request failed! 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Deletion of BST2 Cytoplasmic and Transmembrane N-Terminal Domains Results in SARS-CoV, SARS-CoV-2, and Influenza Virus Production Suppression in a Vero Cell Line |pdf=|usr=}}{{33537341}} gab.com Text Deletion of BST2 Cytoplasmic and Transmembrane N-Terminal Domains Results in SARS-CoV, SARS-CoV-2, and Influenza Virus Production Suppression in a Vero Cell Line JO: Front Mol Biosci http://www.kidney.de/pget.php?&tw=1&pmid=33537341 #FOAvip SARS-CoV-2, which emerged in Wuhan (China), has become a great worldwide problem in 2020 and has led to more than 1,000,000 deaths worldwide. Many laboratories are searching for ways to fight this pandemic. We studied the action of the cellular antiviral protein tetherin, which is encoded by the BST2 gene. We deleted the transmembrane domain-encoding part of the gene in the Vero cell line. The transmembrane domain is a target for virus-antagonizing proteins. We showed a decrease in SARS-CoV-2 in cells with deleted transmembrane BST2 domains compared to the initial Vero cell line. Similar results were obtained for SARS-CoV and avian influenza virus. This finding may help the development of antiviral therapies competitively targeting the transmembrane domain of tetherin with viral-antagonizing proteins. Twit Text FOAVip Deletion of BST2 Cytoplasmic and Transmembrane N-Terminal Domains Results in SARS-CoV, SARS-CoV-2, and Influenza Virus Production Suppression in a Vero Cell Line ????Front Mol Biosci http://www.kidney.de/pget.php?&tw=1&pmid=33537341 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33537341 #FOAvip English Wikipedia <ref>{{Cite pmid|33537341}}</ref> Deletion of BST2 Cytoplasmic and Transmembrane N-Terminal Domains Results in SARS-CoV, SARS-CoV-2, and Influenza Virus Production Suppression in a Vero Cell Line #MMPMID33537341 Dolskiy AA; Bodnev SA; Nazarenko AA; Smirnova AM; Pyankova OG; Matveeva AK; Grishchenko IV; Tregubchak TV; Pyankov OV; Ryzhikov AB; Gavrilova EV; Maksyutov RA; Yudkin DV Front Mol Biosci 2020[]; 7 (ä): 616798 PMID33537341show ga SARS-CoV-2, which emerged in Wuhan (China), has become a great worldwide problem in 2020 and has led to more than 1,000,000 deaths worldwide. Many laboratories are searching for ways to fight this pandemic. We studied the action of the cellular antiviral protein tetherin, which is encoded by the BST2 gene. We deleted the transmembrane domain-encoding part of the gene in the Vero cell line. The transmembrane domain is a target for virus-antagonizing proteins. We showed a decrease in SARS-CoV-2 in cells with deleted transmembrane BST2 domains compared to the initial Vero cell line. Similar results were obtained for SARS-CoV and avian influenza virus. This finding may help the development of antiviral therapies competitively targeting the transmembrane domain of tetherin with viral-antagonizing proteins. äDeletion of BST2 Cytoplasmic and Transmembrane N-Terminal Domains Resu(epmc).pdf DeepDyve Pubget Overpricing