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10.1038/s41598-021-82426-7 http://scihub22266oqcxt.onion/10.1038/s41598-021-82426-7 33536486!7859398!33536486     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2021 ; 11 (1): 2941 Nephropedia Template TP {{tp|p=33536486|t=2021. Dysregulation of lipid metabolism and pathological inflammation in patients with COVID-19 |pdf=|usr=}}{{33536486}} gab.com Text Dysregulation of lipid metabolism and pathological inflammation in patients with COVID-19 JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33536486 #FOAvip In recent months, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world. COVID-19 patients show mild, moderate or severe symptoms with the latter ones requiring access to specialized intensive care. SARS-CoV-2 infections, pathogenesis and progression have not been clearly elucidated yet, thus forcing the development of many complementary approaches to identify candidate cellular pathways involved in disease progression. Host lipids play a critical role in the virus life, being the double-membrane vesicles a key factor in coronavirus replication. Moreover, lipid biogenesis pathways affect receptor-mediated virus entry at the endosomal cell surface and modulate virus propagation. In this study, targeted lipidomic analysis coupled with proinflammatory cytokines and alarmins measurement were carried out in serum of COVID-19 patients characterized by different severity degree. Serum IL-26, a cytokine involved in IL-17 pathway, TSLP and adiponectin were measured and correlated to lipid COVID-19 patient profiles. These results could be important for the classification of the COVID-19 disease and the identification of therapeutic targets. Twit Text FOAVip Dysregulation of lipid metabolism and pathological inflammation in patients with COVID-19 ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33536486 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33536486 #FOAvip English Wikipedia <ref>{{Cite pmid|33536486}}</ref> Dysregulation of lipid metabolism and pathological inflammation in patients with COVID-19 #MMPMID33536486 Caterino M; Gelzo M; Sol S; Fedele R; Annunziata A; Calabrese C; Fiorentino G; D'Abbraccio M; Dell'Isola C; Fusco FM; Parrella R; Fabbrocini G; Gentile I; Andolfo I; Capasso M; Costanzo M; Daniele A; Marchese E; Polito R; Russo R; Missero C; Ruoppolo M; Castaldo G Sci Rep 2021[Feb]; 11 (1): 2941 PMID33536486show ga In recent months, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world. COVID-19 patients show mild, moderate or severe symptoms with the latter ones requiring access to specialized intensive care. SARS-CoV-2 infections, pathogenesis and progression have not been clearly elucidated yet, thus forcing the development of many complementary approaches to identify candidate cellular pathways involved in disease progression. Host lipids play a critical role in the virus life, being the double-membrane vesicles a key factor in coronavirus replication. Moreover, lipid biogenesis pathways affect receptor-mediated virus entry at the endosomal cell surface and modulate virus propagation. In this study, targeted lipidomic analysis coupled with proinflammatory cytokines and alarmins measurement were carried out in serum of COVID-19 patients characterized by different severity degree. Serum IL-26, a cytokine involved in IL-17 pathway, TSLP and adiponectin were measured and correlated to lipid COVID-19 patient profiles. These results could be important for the classification of the COVID-19 disease and the identification of therapeutic targets. |Alarmins/blood[MESH] |COVID-19/*pathology/virology[MESH] |Cytokines/blood[MESH] |Discriminant Analysis[MESH] |Female[MESH] |Humans[MESH] |Least-Squares Analysis[MESH] |Lipid Metabolism/*physiology[MESH] |Lipids/blood[MESH] |Male[MESH] |Middle Aged[MESH] |SARS-CoV-2/isolation & purification[MESH]Dysregulation of lipid metabolism and pathological inflammation in pat(epmc).pdf DeepDyve Pubget Overpricing