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10.1371/journal.pone.0246312

http://scihub22266oqcxt.onion/10.1371/journal.pone.0246312
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33534829!7857607!33534829
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suck abstract from ncbi


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pmid33534829      PLoS+One 2021 ; 16 (2): e0246312
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  • Covid-19 in outpatients-Is fever a useful indicator for SARS-CoV-2 infection? #MMPMID33534829
  • Schneider A; Kirsten H; Lordick F; Lordick F; Lubbert C; von Braun A
  • PLoS One 2021[]; 16 (2): e0246312 PMID33534829show ga
  • OBJECTIVE: Understanding mild to moderate symptoms of coronavirus disease 2019 (Covid-19) is important in order to identify active cases early and thus counteract transmission. METHODS: In March 2020, Leipzig University Hospital established an outpatient clinic for patients potentially infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Confirmed cases with mild to moderate symptoms self-isolated at home and were followed-up by daily telephone calls for at least 14 days. Symptoms and course of illness of these patients are reported here. RESULTS: From March 20 to April 17, 2020, 1460 individuals were tested for SARS-CoV-2 by naso- or oropharyngeal swab for real-time polymerase chain reaction (RT-PCR). Covid-19 was confirmed in 91 (6.2%) patients, of which 87 were included in the final analysis. Patients presented for testing after a mean of 5.9 days (IQR = 2.0-8.5). The median age was 37.0 years (IQR = 28.5-53), and 48 (55.2%) were female. Five (5.7%) patients required hospital admission during the course of illness. Most frequently reported symptoms were fatigue (n = 64, 74%), cough (n = 58, 67%), and hyposmia/hypogeusia (n = 44, 51%). In contrast to previous reports, fever occurred in less than a third of patients (n = 25, 29%). By day 14, more than half of the patients had recovered completely (n = 37/70, 52.9%). CONCLUSIONS: Fever seems to be less common in patients of relatively young age diagnosed with mild to moderate Covid-19. This suggests that body temperature alone may be an insufficient indicator of SARS-CoV-2 infection.
  • |*Body Temperature[MESH]
  • |Adult[MESH]
  • |Anosmia/etiology[MESH]
  • |COVID-19/complications/*diagnosis/virology[MESH]
  • |Cough/etiology[MESH]
  • |Fatigue/etiology[MESH]
  • |Female[MESH]
  • |Hospitalization/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nasopharynx/virology[MESH]
  • |Outpatients[MESH]
  • |RNA, Viral/metabolism[MESH]
  • |Real-Time Polymerase Chain Reaction[MESH]


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