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10.1007/s10096-021-04169-7 http://scihub22266oqcxt.onion/10.1007/s10096-021-04169-7 33534090!7856849!33534090     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Clin+Microbiol+Infect+Dis 2021 ; 40 (5): 1063-1071 Nephropedia Template TP {{tp|p=33534090|t=2021. Sensitivity of anti-SARS-CoV-2 serological assays in a high-prevalence setting |pdf=|usr=}}{{33534090}} gab.com Text Sensitivity of anti-SARS-CoV-2 serological assays in a high-prevalence setting JO: Eur J Clin Microbiol Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33534090 #FOAvip Evaluation and power of seroprevalence studies depend on the performed serological assays. The aim of this study was to assess four commercial serological tests from EUROIMMUN, DiaSorin, Abbott, and Roche as well as an in-house immunofluorescence and neutralization test for their capability to identify SARS-CoV-2 seropositive individuals in a high-prevalence setting. Therefore, 42 social and working contacts of a German super-spreader were tested. Consistent with a high-prevalence setting, 26 of 42 were SARS-CoV-2 seropositive by neutralization test (NT), and immunofluorescence test (IFT) confirmed 23 of these 26 positive test results (NT 61.9% and IFT 54.8% seroprevalence). Four commercial assays detected anti-SARS-CoV-2 antibodies in 33.3-40.5% individuals. Besides an overall discrepancy between the NT and the commercial assays regarding their sensitivity, this study revealed that commercial SARS-CoV-2 spike-based assays are better to predict the neutralization titer than nucleoprotein-based assays are. Twit Text FOAVip Sensitivity of anti-SARS-CoV-2 serological assays in a high-prevalence setting ????Eur J Clin Microbiol Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33534090 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33534090 #FOAvip English Wikipedia <ref>{{Cite pmid|33534090}}</ref> Sensitivity of anti-SARS-CoV-2 serological assays in a high-prevalence setting #MMPMID33534090 Muller L; Ostermann PN; Walker A; Wienemann T; Mertens A; Adams O; Andree M; Hauka S; Lubke N; Keitel V; Drexler I; Di Cristanziano V; Hermsen DF; Kaiser R; Boege F; Klein F; Schaal H; Timm J; Senff T Eur J Clin Microbiol Infect Dis 2021[May]; 40 (5): 1063-1071 PMID33534090show ga Evaluation and power of seroprevalence studies depend on the performed serological assays. The aim of this study was to assess four commercial serological tests from EUROIMMUN, DiaSorin, Abbott, and Roche as well as an in-house immunofluorescence and neutralization test for their capability to identify SARS-CoV-2 seropositive individuals in a high-prevalence setting. Therefore, 42 social and working contacts of a German super-spreader were tested. Consistent with a high-prevalence setting, 26 of 42 were SARS-CoV-2 seropositive by neutralization test (NT), and immunofluorescence test (IFT) confirmed 23 of these 26 positive test results (NT 61.9% and IFT 54.8% seroprevalence). Four commercial assays detected anti-SARS-CoV-2 antibodies in 33.3-40.5% individuals. Besides an overall discrepancy between the NT and the commercial assays regarding their sensitivity, this study revealed that commercial SARS-CoV-2 spike-based assays are better to predict the neutralization titer than nucleoprotein-based assays are. |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Antibodies, Neutralizing/blood[MESH] |Antibodies, Viral/blood[MESH] |COVID-19 Serological Testing/*methods/standards[MESH] |COVID-19/blood/*diagnosis/*epidemiology[MESH] |Contact Tracing[MESH] |Female[MESH] |Humans[MESH] |Immunoassay[MESH] |Male[MESH] |Middle Aged[MESH] |Neutralization Tests[MESH] |Prevalence[MESH] |SARS-CoV-2/immunology/*isolation & purification[MESH] |Sensitivity and Specificity[MESH]Sensitivity of anti-SARS-CoV-2 serological assays in a high-prevalence(epmc).pdf DeepDyve Pubget Overpricing