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10.1002/oby.23142 http://scihub22266oqcxt.onion/10.1002/oby.23142 33533193!8014725!33533193     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Obesity+(Silver+Spring) 2021 ; 29 (5): 870-878 Nephropedia Template TP {{tp|p=33533193|t=2021. Obesity and Critical Illness in COVID-19: Respiratory Pathophysiology |pdf=|usr=}}{{33533193}} gab.com Text Obesity and Critical Illness in COVID-19: Respiratory Pathophysiology JO: Obesity (Silver Spring) http://www.kidney.de/pget.php?&tw=1&pmid=33533193 #FOAvip OBJECTIVE: Recent cohort studies have identified obesity as a risk factor for poor outcomes in coronavirus disease 2019 (COVID-19). To further explore the relationship between obesity and critical illness in COVID-19, the association of BMI with baseline demographic and intensive care unit (ICU) parameters, laboratory values, and outcomes in a critically ill patient cohort was examined. METHODS: In this retrospective study, the first 277 consecutive patients admitted to Massachusetts General Hospital ICUs with laboratory-confirmed COVID-19 were examined. BMI class, initial ICU laboratory values, physiologic characteristics including gas exchange and ventilatory mechanics, and ICU interventions as clinically available were measured. Mortality, length of ICU admission, and duration of mechanical ventilation were also measured. RESULTS: There was no difference found in respiratory system compliance or oxygenation between patients with and without obesity. Patients without obesity had higher initial ferritin and D-dimer levels than patients with obesity. Standard acute respiratory distress syndrome management, including prone ventilation, was equally distributed between BMI groups. There was no difference found in outcomes between BMI groups, including 30- and 60-day mortality and duration of mechanical ventilation. CONCLUSIONS: In this cohort of critically ill patients with COVID-19, obesity was not associated with meaningful differences in respiratory physiology, inflammatory profile, or clinical outcomes. Twit Text FOAVip Obesity and Critical Illness in COVID-19: Respiratory Pathophysiology ????Obesity (Silver Spring) http://www.kidney.de/pget.php?&tw=1&pmid=33533193 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33533193 #FOAvip English Wikipedia <ref>{{Cite pmid|33533193}}</ref> Obesity and Critical Illness in COVID-19: Respiratory Pathophysiology #MMPMID33533193 Wolf M; Alladina J; Navarrete-Welton A; Shoults B; Brait K; Ziehr D; Malhotra A; Hardin CC; Hibbert KA Obesity (Silver Spring) 2021[May]; 29 (5): 870-878 PMID33533193show ga OBJECTIVE: Recent cohort studies have identified obesity as a risk factor for poor outcomes in coronavirus disease 2019 (COVID-19). To further explore the relationship between obesity and critical illness in COVID-19, the association of BMI with baseline demographic and intensive care unit (ICU) parameters, laboratory values, and outcomes in a critically ill patient cohort was examined. METHODS: In this retrospective study, the first 277 consecutive patients admitted to Massachusetts General Hospital ICUs with laboratory-confirmed COVID-19 were examined. BMI class, initial ICU laboratory values, physiologic characteristics including gas exchange and ventilatory mechanics, and ICU interventions as clinically available were measured. Mortality, length of ICU admission, and duration of mechanical ventilation were also measured. RESULTS: There was no difference found in respiratory system compliance or oxygenation between patients with and without obesity. Patients without obesity had higher initial ferritin and D-dimer levels than patients with obesity. Standard acute respiratory distress syndrome management, including prone ventilation, was equally distributed between BMI groups. There was no difference found in outcomes between BMI groups, including 30- and 60-day mortality and duration of mechanical ventilation. CONCLUSIONS: In this cohort of critically ill patients with COVID-19, obesity was not associated with meaningful differences in respiratory physiology, inflammatory profile, or clinical outcomes. |*Body Mass Index[MESH] |Aged[MESH] |COVID-19/*complications/epidemiology[MESH] |Critical Illness[MESH] |Female[MESH] |Hospitalization[MESH] |Humans[MESH] |Intensive Care Units[MESH] |Male[MESH] |Massachusetts[MESH] |Middle Aged[MESH] |Obesity/*complications[MESH] |Respiration, Artificial[MESH] |Retrospective Studies[MESH]Obesity and Critical Illness in COVID-19: Respiratory Pathophysiology (epmc).pdf DeepDyve Pubget Overpricing