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10.1002/jgm.3318 http://scihub22266oqcxt.onion/10.1002/jgm.3318 33533071!7988597!33533071     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\33533071.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Gene+Med 2021 ; 23 (3): e3318 Nephropedia Template TP {{tp|p=33533071|t=2021. Long non-coding RNAs: Promising new targets in pulmonary fibrosis |pdf=|usr=}}{{33533071}} gab.com Text Long non-coding RNAs: Promising new targets in pulmonary fibrosis JO: J Gene Med http://www.kidney.de/pget.php?&tw=1&pmid=33533071 #FOAvip Pulmonary fibrosis is characterized by progressive and irreversible scarring in the lungs with poor prognosis and treatment. It is caused by various factors, including environmental and occupational exposures, and some rheumatic immune diseases. Even the rapid global spread of the COVID-19 pandemic can also cause pulmonary fibrosis with a high probability. Functions attributed to long non-coding RNAs (lncRNAs) make them highly attractive diagnostic and therapeutic targets in fibroproliferative diseases. Therefore, an understanding of the specific mechanisms by which lncRNAs regulate pulmonary fibrotic pathogenesis is urgently needed to identify new possibilities for therapy. In this review, we focus on the molecular mechanisms and implications of lncRNAs targeted protein-coding and non-coding genes during pulmonary fibrogenesis, and systematically analyze the communication of lncRNAs with various types of RNAs, including microRNA, circular RNA and mRNA. Finally, we propose the potential approach of lncRNA-based diagnosis and therapy for pulmonary fibrosis. We hope that understanding these interactions between protein-coding and non-coding genes will contribute to the development of lncRNA-based clinical applications for pulmonary fibrosis. Twit Text FOAVip Long non-coding RNAs: Promising new targets in pulmonary fibrosis ????J Gene Med http://www.kidney.de/pget.php?&tw=1&pmid=33533071 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33533071 #FOAvip English Wikipedia <ref>{{Cite pmid|33533071}}</ref> Long non-coding RNAs: Promising new targets in pulmonary fibrosis #MMPMID33533071 Zhang S; Chen H; Yue D; Blackwell TS; Lv C; Song X J Gene Med 2021[Mar]; 23 (3): e3318 PMID33533071show ga Pulmonary fibrosis is characterized by progressive and irreversible scarring in the lungs with poor prognosis and treatment. It is caused by various factors, including environmental and occupational exposures, and some rheumatic immune diseases. Even the rapid global spread of the COVID-19 pandemic can also cause pulmonary fibrosis with a high probability. Functions attributed to long non-coding RNAs (lncRNAs) make them highly attractive diagnostic and therapeutic targets in fibroproliferative diseases. Therefore, an understanding of the specific mechanisms by which lncRNAs regulate pulmonary fibrotic pathogenesis is urgently needed to identify new possibilities for therapy. In this review, we focus on the molecular mechanisms and implications of lncRNAs targeted protein-coding and non-coding genes during pulmonary fibrogenesis, and systematically analyze the communication of lncRNAs with various types of RNAs, including microRNA, circular RNA and mRNA. Finally, we propose the potential approach of lncRNA-based diagnosis and therapy for pulmonary fibrosis. We hope that understanding these interactions between protein-coding and non-coding genes will contribute to the development of lncRNA-based clinical applications for pulmonary fibrosis. |Gene Expression Regulation[MESH] |Genetic Markers/*genetics[MESH] |Genetic Therapy/methods[MESH] |Humans[MESH] |MicroRNAs/genetics[MESH] |Proteins/genetics[MESH] |Pulmonary Fibrosis/diagnosis/*genetics/pathology/therapy[MESH] |RNA, Circular/genetics[MESH]Long non-coding RNAs: Promising new targets in pulmonary fibrosis (epmc).pdf DeepDyve Pubget Overpricing