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10.3390/ijms22031213

http://scihub22266oqcxt.onion/10.3390/ijms22031213
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33530554!7866163!33530554
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suck abstract from ncbi


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pmid33530554      Int+J+Mol+Sci 2021 ; 22 (3): ä
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  • Mediterranean Diet for the Prevention of Gestational Diabetes in the Covid-19 Era: Implications of Il-6 In Diabesity #MMPMID33530554
  • Fedullo AL; Schiattarella A; Morlando M; Raguzzini A; Toti E; De Franciscis P; Peluso I
  • Int J Mol Sci 2021[Jan]; 22 (3): ä PMID33530554show ga
  • The aim of this review is to highlight the influence of the Mediterranean Diet (MedDiet) on Gestational Diabetes Mellitus (GDM) and Gestational Weight Gain (GWG) during the COVID-19 pandemic era and the specific role of interleukin (IL)-6 in diabesity. It is known that diabetes, high body mass index, high glycated hemoglobin and raised serum IL-6 levels are predictive of poor outcomes in coronavirus disease 2019 (COVID-19). The immunopathological mechanisms of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection include rising levels of several cytokines and in particular IL-6. The latter is associated with hyperglycemia and insulin resistance and could be useful for predicting the development of GDM. Rich in omega-3 polyunsaturated fatty acids, vitamins, and minerals, MedDiet improves the immune system and could modulate IL-6, C reactive protein and Nuclear Factor (NF)-kappaB. Moreover, polyphenols could modulate microbiota composition, inhibit the NF-kappaB pathway, lower IL-6, and upregulate antioxidant enzymes. Finally, adhering to the MedDiet prior to and during pregnancy could have a protective effect, reducing GWG and the risk of GDM, as well as improving the immune response to viral infections such as COVID-19.
  • |*Diet, Mediterranean[MESH]
  • |Animals[MESH]
  • |COVID-19/*blood/epidemiology[MESH]
  • |Diabetes, Gestational/blood/epidemiology/*prevention & control[MESH]
  • |Female[MESH]
  • |Gestational Weight Gain[MESH]
  • |Humans[MESH]
  • |Interleukin-6/*blood[MESH]
  • |Life Style[MESH]
  • |Obesity/blood/epidemiology/prevention & control[MESH]


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