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Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Allergol+Immunopathol+(Madr) 2021 ; 49 (1): 113-117 Nephropedia Template TP
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Inhaled corticosteroids may have a protective effect against coronavirus infection #MMPMID33528938
Armentia A; Cortes SF; Simon AM; Martin-Armentia B; Martin-Armentia S; Pollo DR; Canadas JCN; Cano JV; Rubiales AS; Fra JR; Vaquero SG; Pazos MC; de la Calle JG; Lowell ER; Soto CC; Toledano CS; Salgado AS
Allergol Immunopathol (Madr) 2021[]; 49 (1): 113-117 PMID33528938show ga
BACKGROUND: Spain has been severely affected by the COVID-19 epidemic, with 195,944 persons infected and 20,453 deaths at the time of writing. Older people with respiratory or cardiac conditions are most at risk. OBJECTIVE: The aim was to compare respiratory symptoms in nursing home residents and patients with uncontrolled asthma, who are considered vulnerable to COVID-19. METHODS: We studied 134 nursing home residents and 139 patients with uncontrolled asthma, groups vulnerable to COVID-19. Demographic characteristics, clinical manifestations, outcomes, key laboratory results, and radiological images were collected from medical records. COVID-19 infection was detected by polymerase chain reaction (PCR). RESULTS: Thirteen (9.3%) patients with uncontrolled asthma, all receiving inhaled corticosteroids were infected by COVID-19. Eighty (60%) nursing home residents were infected; only 28, all of whom had received inhaled corticosteroids, had a good prognosis. CONCLUSIONS: Early treatment with inhaled corticosteroids may be helpful in COVID-19 infection. Persons with an allergy might have some protective mechanisms against coronavirus.