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10.1177/2150132720987711

http://scihub22266oqcxt.onion/10.1177/2150132720987711
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33525985!7970702!33525985
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suck abstract from ncbi


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pmid33525985      J+Prim+Care+Community+Health 2021 ; 12 (ä): 2150132720987711
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  • Acceptance of a Symptom-Based Approach for COVID-19 rtRT-PCR Testing to Conserve Resources in a Lower Middle-Income Setting #MMPMID33525985
  • Islam SMRU; Akther T; Nasif MAO; Sultana S; Munshi SU
  • J Prim Care Community Health 2021[Jan]; 12 (ä): 2150132720987711 PMID33525985show ga
  • SARS-CoV-2 initially emerged in Wuhan, China in late 2019. It has since been recognized as a pandemic and has led to great social and economic disruption globally. The Reverse Transcriptase Real-Time Polymerase Chain Reaction (rtRT-PCR) has become the primary method for COVID-19 testing worldwide. The method requires a specialized laboratory set up. Long-term persistence of SARS-CoV-2 RNA in nasopharyngeal secretion after full clinical recovery of the patient is regularly observed nowadays. This forces the patients to spend a longer period in isolation and test repeatedly to obtain evidence of viral clearance. Repeated COVID-19 testing in asymptomatic or mildly symptomatic cases often leads to extra workload for laboratories that are already struggling with a high specimen turnover. Here, we present 5 purposively selected cases with different patterns of clinical presentations in which nasopharyngeal shedding of SARS-CoV-2 RNA was observed in patients for a long time. From these case studies, we emphasized the adoption of a symptom-based approach for discontinuing transmission-based precautions over a test-based strategy to reduce the time spent by asymptomatic and mildly symptomatic COVID-19 patients in isolation. A symptom-based approach will also help reduce laboratory burden for COVID-19 testing as well as conserve valuable resources and supplies utilized for rtRT-PCR testing in an emerging lower-middle-income setting. Most importantly, it will also make room for critically ill COVID-19 patients to visit or avail COVID-19 testing at their convenience.
  • |*Symptom Assessment[MESH]
  • |Adult[MESH]
  • |COVID-19 Testing/*methods/statistics & numerical data[MESH]
  • |COVID-19/complications/*diagnosis[MESH]
  • |Developing Countries[MESH]
  • |Female[MESH]
  • |Health Care Rationing/*methods[MESH]
  • |Humans[MESH]
  • |Laboratories/statistics & numerical data[MESH]
  • |Male[MESH]
  • |Patient Isolation/statistics & numerical data[MESH]
  • |RNA, Viral/isolation & purification[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2/genetics/isolation & purification[MESH]


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