Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.snb.2020.129333 http://scihub22266oqcxt.onion/10.1016/j.snb.2020.129333 33519090!7833127!33519090     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sens+Actuators+B+Chem 2021 ; 330 (ä): 129333 Nephropedia Template TP {{tp|p=33519090|t=2021. Paper biosensors for detecting elevated IL-6 levels in blood and respiratory samples from COVID-19 patients |pdf=|usr=}}{{33519090}} gab.com Text Paper biosensors for detecting elevated IL-6 levels in blood and respiratory samples from COVID-19 patients JO: Sens Actuators B Chem http://www.kidney.de/pget.php?&tw=1&pmid=33519090 #FOAvip Decentralizing COVID-19 care reduces contagions and affords a better use of hospital resources. We introduce biosensors aimed at detecting severe cases of COVID-19 in decentralized healthcare settings. They consist of a paper immunosensor interfaced with a smartphone. The immunosensors have been designed to generate intense colorimetric signals when the sample contains ultralow concentrations of IL-6, which has been proposed as a prognosis biomarker of COVID-19. This is achieved by combining a paper-based signal amplification mechanism with polymer-filled reservoirs for dispensing antibody-decorated nanoparticles and a bespoken app for color quantification. With this design we achieved a low limit of detection (LOD) of 10(-3) pg mL(-1) and semi-quantitative measurements in a wide dynamic range between 10(-3) and 10(2) pg mL(-1) in PBS. The assay time is under 10 min. The low LOD allowed us to dilute blood samples and detect IL-6 with an LOD of 1.3 pg mL(-1) and a dynamic range up to 10(2) pg mL(-1). Following this protocol, we were able to stratify COVID-19 patients according to different blood levels of IL-6. We also report on the detection of IL-6 in respiratory samples (bronchial aspirate, BAS) from COVID-19 patients. The test could be easily adapted to detect other cytokines such as TNF-alpha and IL-8 by changing the antibodies decorating the nanoparticles accordingly. The ability of detecting cytokines in blood and respiratory samples paves the way for monitoring local inflammation in the lungs as well as systemic inflammation levels in the body. Twit Text FOAVip Paper biosensors for detecting elevated IL-6 levels in blood and respiratory samples from COVID-19 patients ????Sens Actuators B Chem http://www.kidney.de/pget.php?&tw=1&pmid=33519090 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33519090 #FOAvip English Wikipedia <ref>{{Cite pmid|33519090}}</ref> Paper biosensors for detecting elevated IL-6 levels in blood and respiratory samples from COVID-19 patients #MMPMID33519090 Adrover-Jaume C; Alba-Patino A; Clemente A; Santopolo G; Vaquer A; Russell SM; Baron E; Gonzalez Del Campo MDM; Ferrer JM; Berman-Riu M; Garcia-Gasalla M; Aranda M; Borges M; de la Rica R Sens Actuators B Chem 2021[Mar]; 330 (ä): 129333 PMID33519090show ga Decentralizing COVID-19 care reduces contagions and affords a better use of hospital resources. We introduce biosensors aimed at detecting severe cases of COVID-19 in decentralized healthcare settings. They consist of a paper immunosensor interfaced with a smartphone. The immunosensors have been designed to generate intense colorimetric signals when the sample contains ultralow concentrations of IL-6, which has been proposed as a prognosis biomarker of COVID-19. This is achieved by combining a paper-based signal amplification mechanism with polymer-filled reservoirs for dispensing antibody-decorated nanoparticles and a bespoken app for color quantification. With this design we achieved a low limit of detection (LOD) of 10(-3) pg mL(-1) and semi-quantitative measurements in a wide dynamic range between 10(-3) and 10(2) pg mL(-1) in PBS. The assay time is under 10 min. The low LOD allowed us to dilute blood samples and detect IL-6 with an LOD of 1.3 pg mL(-1) and a dynamic range up to 10(2) pg mL(-1). Following this protocol, we were able to stratify COVID-19 patients according to different blood levels of IL-6. We also report on the detection of IL-6 in respiratory samples (bronchial aspirate, BAS) from COVID-19 patients. The test could be easily adapted to detect other cytokines such as TNF-alpha and IL-8 by changing the antibodies decorating the nanoparticles accordingly. The ability of detecting cytokines in blood and respiratory samples paves the way for monitoring local inflammation in the lungs as well as systemic inflammation levels in the body. äPaper biosensors for detecting elevated IL-6 levels in blood and respi(epmc).pdf DeepDyve Pubget Overpricing