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10.1016/j.plefa.2021.102250

http://scihub22266oqcxt.onion/10.1016/j.plefa.2021.102250
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33516093!7816864!33516093
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suck abstract from ncbi


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pmid33516093      Prostaglandins+Leukot+Essent+Fatty+Acids 2021 ; 166 (ä): 102250
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  • Blood omega-3 fatty acids and death from COVID-19: A pilot study #MMPMID33516093
  • Asher A; Tintle NL; Myers M; Lockshon L; Bacareza H; Harris WS
  • Prostaglandins Leukot Essent Fatty Acids 2021[Mar]; 166 (ä): 102250 PMID33516093show ga
  • Very-long chain omega-3 fatty acids (EPA and DHA) have anti-inflammatory properties that may help reduce morbidity and mortality from COVID-19 infection. We conducted a pilot study in 100 patients to test the hypothesis that RBC EPA+DHA levels (the Omega-3 Index, O3I) would be inversely associated with risk for death by analyzing the O3I in banked blood samples drawn at hospital admission. Fourteen patients died, one of 25 in quartile 4 (Q4) (O3I >/=5.7%) and 13 of 75 in Q1-3. After adjusting for age and sex, the odds ratio for death in patients with an O3I in Q4 vs Q1-3 was 0.25, p = 0.07. Although not meeting the classical criteria for statistical significance, this strong trend suggests that a relationship may indeed exist, but more well-powered studies are clearly needed.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*blood/*mortality[MESH]
  • |Docosahexaenoic Acids/blood[MESH]
  • |Eicosapentaenoic Acid/blood[MESH]
  • |Erythrocytes/metabolism[MESH]
  • |Fatty Acids, Omega-3/*blood[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pilot Projects[MESH]


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