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10.1016/j.bios.2021.113029 http://scihub22266oqcxt.onion/10.1016/j.bios.2021.113029 33515985!7826012!33515985     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biosens+Bioelectron 2021 ; 178 (ä): 113029 Nephropedia Template TP {{tp|p=33515985|t=2021. Development of a portable MIP-based electrochemical sensor for detection of SARS-CoV-2 antigen |pdf=|usr=}}{{33515985}} gab.com Text Development of a portable MIP-based electrochemical sensor for detection of SARS-CoV-2 antigen JO: Biosens Bioelectron http://www.kidney.de/pget.php?&tw=1&pmid=33515985 #FOAvip The current COVID-19 pandemic caused by SARS-CoV-2 coronavirus is expanding around the globe. Hence, accurate and cheap portable sensors are crucially important for the clinical diagnosis of COVID-19. Molecularly imprinted polymers (MIPs) as robust synthetic molecular recognition materials with antibody-like ability to bind and discriminate between molecules can perfectly serve in building selective elements in such sensors. Herein, we report for the first time on the development of a MIP-based electrochemical sensor for detection of SARS-CoV-2 nucleoprotein (ncovNP). A key element of the sensor is a disposable sensor chip - thin film electrode - interfaced with a MIP-endowed selectivity for ncovNP and connected with a portable potentiostat. The resulting ncovNP sensor showed a linear response to ncovNP in the lysis buffer up to 111 fM with a detection and quantification limit of 15 fM and 50 fM, respectively. Notably, the sensor was capable of signaling ncovNP presence in nasopharyngeal swab samples of COVID-19 positive patients. The presented strategy unlocks a new route for the development of rapid COVID-19 diagnostic tools. Twit Text FOAVip Development of a portable MIP-based electrochemical sensor for detection of SARS-CoV-2 antigen ????Biosens Bioelectron http://www.kidney.de/pget.php?&tw=1&pmid=33515985 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33515985 #FOAvip English Wikipedia <ref>{{Cite pmid|33515985}}</ref> Development of a portable MIP-based electrochemical sensor for detection of SARS-CoV-2 antigen #MMPMID33515985 Raziq A; Kidakova A; Boroznjak R; Reut J; Opik A; Syritski V Biosens Bioelectron 2021[Apr]; 178 (ä): 113029 PMID33515985show ga The current COVID-19 pandemic caused by SARS-CoV-2 coronavirus is expanding around the globe. Hence, accurate and cheap portable sensors are crucially important for the clinical diagnosis of COVID-19. Molecularly imprinted polymers (MIPs) as robust synthetic molecular recognition materials with antibody-like ability to bind and discriminate between molecules can perfectly serve in building selective elements in such sensors. Herein, we report for the first time on the development of a MIP-based electrochemical sensor for detection of SARS-CoV-2 nucleoprotein (ncovNP). A key element of the sensor is a disposable sensor chip - thin film electrode - interfaced with a MIP-endowed selectivity for ncovNP and connected with a portable potentiostat. The resulting ncovNP sensor showed a linear response to ncovNP in the lysis buffer up to 111 fM with a detection and quantification limit of 15 fM and 50 fM, respectively. Notably, the sensor was capable of signaling ncovNP presence in nasopharyngeal swab samples of COVID-19 positive patients. The presented strategy unlocks a new route for the development of rapid COVID-19 diagnostic tools. |Antigens, Viral/*analysis[MESH] |Biosensing Techniques/*instrumentation[MESH] |COVID-19 Testing/*instrumentation[MESH] |COVID-19/*diagnosis/*virology[MESH] |Coronavirus Nucleocapsid Proteins/*analysis/*immunology[MESH] |Electrochemical Techniques/instrumentation[MESH] |Equipment Design[MESH] |Feasibility Studies[MESH] |Humans[MESH] |Molecular Imprinting[MESH] |Nasopharynx/virology[MESH] |Pandemics[MESH] |Phosphoproteins/analysis/immunology[MESH] |Polymers[MESH]Development of a portable MIP-based electrochemical sensor for detecti(epmc).pdf DeepDyve Pubget Overpricing