B cell memory: understanding COVID-19 #MMPMID33513337
Quast I; Tarlinton D
Immunity 2021[Feb]; 54 (2): 205-210 PMID33513337show ga
Immunological memory is a mechanism to protect us against reinfection. Antibodies produced by B cells are integral to this defense strategy and underlie virtually all vaccine success. Here, we explain how B cells memory is generated by infection and vaccination, what influences its efficacy and its persistence, and how characterizing these parameters in the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will help achieve protective immunity through vaccination.