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10.1371/journal.pone.0246326

http://scihub22266oqcxt.onion/10.1371/journal.pone.0246326
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33513204!7845974!33513204
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suck abstract from ncbi


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pmid33513204      PLoS+One 2021 ; 16 (1): e0246326
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  • The differential impact of pediatric COVID-19 between high-income countries and low- and middle-income countries: A systematic review of fatality and ICU admission in children worldwide #MMPMID33513204
  • Kitano T; Kitano M; Krueger C; Jamal H; Al Rawahi H; Lee-Krueger R; Sun RD; Isabel S; Garcia-Ascaso MT; Hibino H; Camara B; Isabel M; Cho L; Groves HE; Piche-Renaud PP; Kossov M; Kou I; Jon I; Blanchard AC; Matsuda N; Mahood Q; Wadhwa A; Bitnun A; Morris SK
  • PLoS One 2021[]; 16 (1): e0246326 PMID33513204show ga
  • BACKGROUND: The overall global impact of COVID-19 in children and regional variability in pediatric outcomes are presently unknown. METHODS: To evaluate the magnitude of global COVID-19 death and intensive care unit (ICU) admission in children aged 0-19 years, a systematic review was conducted for articles and national reports as of December 7, 2020. This systematic review is registered with PROSPERO (registration number: CRD42020179696). RESULTS: We reviewed 16,027 articles as well as 225 national reports from 216 countries. Among the 3,788 global pediatric COVID-19 deaths, 3,394 (91.5%) deaths were reported from low- and middle-income countries (LMIC), while 83.5% of pediatric population from all included countries were from LMIC. The pediatric deaths/1,000,000 children and case fatality rate (CFR) were significantly higher in LMIC than in high-income countries (HIC) (2.77 in LMIC vs 1.32 in HIC; p < 0.001 and 0.24% in LMIC vs 0.01% in HIC; p < 0.001, respectively). The ICU admission/1,000,000 children was 18.80 and 1.48 in HIC and LMIC, respectively (p < 0.001). The highest deaths/1,000,000 children and CFR were in infants < 1 year old (10.03 and 0.58% in the world, 5.39 and 0.07% in HIC and 10.98 and 1.30% in LMIC, respectively). CONCLUSIONS: The study highlights that there may be a larger impact of pediatric COVID-19 fatality in LMICs compared to HICs.
  • |*Socioeconomic Factors[MESH]
  • |Age Factors[MESH]
  • |COVID-19/*epidemiology/mortality[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Global Health/*economics[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Infant, Newborn[MESH]
  • |Intensive Care Units[MESH]
  • |Pandemics[MESH]


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