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10.1007/s12020-021-02619-y

http://scihub22266oqcxt.onion/10.1007/s12020-021-02619-y
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33512658!7845285!33512658
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suck abstract from ncbi


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pmid33512658      Endocrine 2021 ; 71 (3): 653-662
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  • Clinical management of patients with genetic obesity during COVID-19 pandemic: position paper of the ESE Growth & Genetic Obesity COVID-19 Study Group and Rare Endo-ERN main thematic group on Growth and Obesity #MMPMID33512658
  • De Groot CJ; Poitou Bernert C; Coupaye M; Clement K; Paschou SA; Charmandari E; Kanaka-Gantenbein C; Wabitsch M; Buddingh EP; Nieuwenhuijsen B; Marina L; Johannsson G; Van Den Akker ELT
  • Endocrine 2021[Mar]; 71 (3): 653-662 PMID33512658show ga
  • This article aims to provide guidance on prevention and treatment of COVID-19 in patients with genetic obesity. Key principals of the management of patients with genetic obesity during COVID-19 pandemic for patients that have contracted COVID-19 are to be aware of: possible adrenal insufficiency (e.g., POMC deficiency, PWS); a more severe course in patients with concomitant immunodeficiency (e.g., LEP and LEPR deficiency), although defective leptin signalling could also be protective against the pro-inflammatory phenotype of COVID-19; disease severity being masked by insufficient awareness of symptoms in syndromic obesity patients with intellectual deficit (in particular PWS); to adjust medication dose to increased body size, preferably use dosing in m2; the high risk of malnutrition in patients with Sars-Cov2 infection, even in case of obesity. Key principals of the obesity management during the pandemic are to strive for optimal obesity management and a healthy lifestyle within the possibilities of the regulations to prevent weight (re)gain and to address anxiety within consultations, since prevalence of anxiety for COVID-19 is underestimated.
  • |*COVID-19[MESH]
  • |*Disease Management[MESH]
  • |*Pandemics[MESH]
  • |Anxiety[MESH]
  • |Healthy Lifestyle[MESH]
  • |Humans[MESH]


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