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10.1002/jmv.26823

http://scihub22266oqcxt.onion/10.1002/jmv.26823
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33506970!8013853!33506970
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suck abstract from ncbi


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pmid33506970      J+Med+Virol 2021 ; 93 (5): 2566-2568
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  • Will the emergent SARS-CoV2 B 1 1 7 lineage affect molecular diagnosis of COVID-19? #MMPMID33506970
  • Ramirez JD; Munoz M; Patino LH; Ballesteros N; Paniz-Mondolfi A
  • J Med Virol 2021[May]; 93 (5): 2566-2568 PMID33506970show ga
  • As the coronavirus disease 2019 pandemic keep tackling global public health systems worldwide. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) genome keeps mutating. In that regard, the recent emergence of the B.1.1.7 lineage in the UK has called the attention of global authorities. One point of concern is that if this lineage can be detected by traditional molecular schemes for SARS-CoV-2 detection. Herein, we showed that this lineage does not affect the Berlin-Charite protocol but can challenge the available commercial kits directed to the Spike (S) gene. All efforts should be made to continue to monitor SARS-CoV-2 genomes for potential variants that can impair diagnostic testing and lead to false negative results.
  • |*COVID-19 Nucleic Acid Testing[MESH]
  • |COVID-19/*diagnosis/epidemiology[MESH]
  • |Genetic Variation[MESH]
  • |Genome, Viral/genetics[MESH]
  • |Humans[MESH]
  • |SARS-CoV-2/*genetics/*isolation & purification[MESH]
  • |Sensitivity and Specificity[MESH]


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