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10.1002/jmv.26827 http://scihub22266oqcxt.onion/10.1002/jmv.26827 33506950!8013331!33506950     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Med+Virol 2021 ; 93 (5): 2979-2987 Nephropedia Template TP {{tp|p=33506950|t=2021. Clinical significance of cellular immunity function and inflammatory factors assays in alveolar lavage fluid for severe COVID-19 pneumonia |pdf=|usr=}}{{33506950}} gab.com Text Clinical significance of cellular immunity function and inflammatory factors assays in alveolar lavage fluid for severe COVID-19 pneumonia JO: J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=33506950 #FOAvip In this study, we aimed to investigate the changes of lymphocyte subsets (CD3(+) , CD4(+) , CD8(+) ) and inflammatory factors (interleukin-6 [IL-6], hypersensitive C-reactive protein [HS-CRP], and procalcitonin [PCT]) of alveolar lavage fluid in patients with severe corona virus-2019 (COVID-19) pneumonia and their clinical impact on the assessment of disease severity and prognosis. Twenty-four patients with severe COVID-19 pneumonia were admitted to the intensive care unit (ICU) of the Ezhou Central Hospital from February 1 to March 22, 2020. According to the 28-day prognosis, they were assigned to a death group and a survival group. On the 3rd day of ICU admission, peripheral blood and alveolar lavage fluid were collected for examination of lymphocyte subsets and inflammatory factors by flow cytometry and immunoturbidimetry, respectively. The CD3(+) , CD4(+) , and CD8(+) cell counts in alveolar lavage fluid and serum were significantly higher in the survival group than those of the death group (p < .05). The levels of IL-6, HS-CRP, and PCT in the alveolar lavage fluid and serum of the death group were statistically higher than those of the survival group (p < .05); The CD3(+) , CD4(+) cell count, and IL-6 level were negatively correlated with Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation II scores, respectively (p < .05). The CD4(+) cell and SOFA score have a regression relationship for the prognosis of COVID-19 severe patients. The CD3(+) , CD4(+) , CD8(+) cells, and IL-6 levels are valuable in determining the prognosis of severe COVID-19 pneumonia and are strongly correlated with the severity of the disease; the CD4(+) cell is an independent risk factor affecting the prognosis of COVID-19 pneumonia. Twit Text FOAVip Clinical significance of cellular immunity function and inflammatory factors assays in alveolar lavage fluid for severe COVID-19 pneumonia ????J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=33506950 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33506950 #FOAvip English Wikipedia <ref>{{Cite pmid|33506950}}</ref> Clinical significance of cellular immunity function and inflammatory factors assays in alveolar lavage fluid for severe COVID-19 pneumonia #MMPMID33506950 Liao L; Yang GH J Med Virol 2021[May]; 93 (5): 2979-2987 PMID33506950show ga In this study, we aimed to investigate the changes of lymphocyte subsets (CD3(+) , CD4(+) , CD8(+) ) and inflammatory factors (interleukin-6 [IL-6], hypersensitive C-reactive protein [HS-CRP], and procalcitonin [PCT]) of alveolar lavage fluid in patients with severe corona virus-2019 (COVID-19) pneumonia and their clinical impact on the assessment of disease severity and prognosis. Twenty-four patients with severe COVID-19 pneumonia were admitted to the intensive care unit (ICU) of the Ezhou Central Hospital from February 1 to March 22, 2020. According to the 28-day prognosis, they were assigned to a death group and a survival group. On the 3rd day of ICU admission, peripheral blood and alveolar lavage fluid were collected for examination of lymphocyte subsets and inflammatory factors by flow cytometry and immunoturbidimetry, respectively. The CD3(+) , CD4(+) , and CD8(+) cell counts in alveolar lavage fluid and serum were significantly higher in the survival group than those of the death group (p < .05). The levels of IL-6, HS-CRP, and PCT in the alveolar lavage fluid and serum of the death group were statistically higher than those of the survival group (p < .05); The CD3(+) , CD4(+) cell count, and IL-6 level were negatively correlated with Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation II scores, respectively (p < .05). The CD4(+) cell and SOFA score have a regression relationship for the prognosis of COVID-19 severe patients. The CD3(+) , CD4(+) , CD8(+) cells, and IL-6 levels are valuable in determining the prognosis of severe COVID-19 pneumonia and are strongly correlated with the severity of the disease; the CD4(+) cell is an independent risk factor affecting the prognosis of COVID-19 pneumonia. |Adult[MESH] |Aged[MESH] |Biomarkers/metabolism[MESH] |Bronchoalveolar Lavage Fluid/*immunology[MESH] |COVID-19/diagnosis/*immunology/*pathology[MESH] |Female[MESH] |Humans[MESH] |Immunity, Cellular[MESH] |Inflammation[MESH] |Intensive Care Units[MESH] |Lymphocyte Count[MESH] |Lymphocyte Subsets/cytology[MESH] |Male[MESH] |Middle Aged[MESH] |Prognosis[MESH] |ROC Curve[MESH] |SARS-CoV-2[MESH]Clinical significance of cellular immunity function and inflammatory f(epmc).pdf DeepDyve Pubget Overpricing