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10.1007/s00066-020-01743-4

http://scihub22266oqcxt.onion/10.1007/s00066-020-01743-4
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suck abstract from ncbi


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pmid33502567      Strahlenther+Onkol 2021 ; 197 (5): 429-437
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  • COVID-19 pneumonia treated with ultra-low doses of radiotherapy (ULTRA-COVID study): a single institution report of two cases #MMPMID33502567
  • Moreno-Olmedo E; Suarez-Gironzini V; Perez M; Filigheddu T; Minguez C; Sanjuan-Sanjuan A; Gonzalez JA; Rivas D; Gorospe L; Larrea L; Lopez E
  • Strahlenther Onkol 2021[May]; 197 (5): 429-437 PMID33502567show ga
  • INTRODUCTION: Since the outbreak of coronavirus disease 2019 (COVID-19) pandemic, healthcare systems have focused their efforts into finding a treatment to avoid the fatal outcomes of severe acute respiratory syndrome due to coronavirus?2 (SARS-CoV-2). Benefits and risks of systemic treatments remain unclear, with multiple clinical trials still ongoing. Radiotherapy could play a role in reducing the inflammatory response in the lungs and relieve life-threatening symptoms. METHODS: We designed a prospective study of Ultra-Low Doses of Therapy with Radiation Applied to COVID-19 (ULTRA-COVID) for patients who suffer pneumonia, are not candidates for invasive mechanical ventilation and show no improvement with medical therapy. RESULTS: We present the preliminary results of two patients diagnosed with COVID-19 pneumonia treated with ULTRA-COVID. After one radiotherapy session, significant clinical response and a good radiological response was observed in both cases, resulting in both patients being discharged from hospital in less than 2 weeks after radiation treatment. CONCLUSION: Preliminary clinical and radiological results suggest a potential benefit of treating COVID-19 pneumonia with ULTRA-COVID. ClinicalTrials.gov Identifier: NCT04394182.
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/pathology/*radiotherapy[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Preliminary Data[MESH]
  • |Prospective Studies[MESH]
  • |Radiotherapy Dosage[MESH]
  • |Radiotherapy/methods[MESH]
  • |SARS-CoV-2/*radiation effects[MESH]


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