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10.1007/s13205-021-02647-5 http://scihub22266oqcxt.onion/10.1007/s13205-021-02647-5 33500874!7820838!33500874     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       3+Biotech 2021 ; 11 (2): 89 Nephropedia Template TP {{tp|p=33500874|t=2021. Perspective on therapeutic and diagnostic potential of camel nanobodies for coronavirus disease-19 (COVID-19) |pdf=|usr=}}{{33500874}} gab.com Text Perspective on therapeutic and diagnostic potential of camel nanobodies for coronavirus disease-19 (COVID-19) JO: 3 Biotech http://www.kidney.de/pget.php?&tw=1&pmid=33500874 #FOAvip In this paper, we focus on the camelid nanobodies as a revolutionary therapy that can guide efforts to discover new drugs for Coronavirus disease (COVID-19). The small size property makes nanobodies capable of penetrating efficiently into tissues and recognizing cryptic antigens. Strong antigen affinity and stability in the gastrointestinal tract allow them to be used via oral administration. In fact, the use of nanobodies as inhalant can be directly delivered to the target organ, conferring high pulmonary drug concentrations and low systemic drug concentrations and minimal systemic side effects. For that, nanobodies are referred as a class of next-generation antibodies. Nanobodies permit the construction of multivalent formats that may achieve ultra-high neutralization potency and then may prevent mutational escape and can neutralize a wide range of SARS-CoV-2 variants. Due to their distinctive characteristics, nanobodies can be of great use in the development of promising treatment or preventive strategies against SARS-CoV-2 infection. In this review, the state-of-the-art of camel nanobodies design strategies against the virus including SARS-CoV-2 are critically summarized. The application of general nanotechnology was also discussed to mitigate and control emerging SARS-CoV-2 infection. Twit Text FOAVip Perspective on therapeutic and diagnostic potential of camel nanobodies for coronavirus disease-19 (COVID-19) ????3 Biotech http://www.kidney.de/pget.php?&tw=1&pmid=33500874 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33500874 #FOAvip English Wikipedia <ref>{{Cite pmid|33500874}}</ref> Perspective on therapeutic and diagnostic potential of camel nanobodies for coronavirus disease-19 (COVID-19) #MMPMID33500874 Bessalah S; Jebahi S; Mejri N; Salhi I; Khorchani T; Hammadi M 3 Biotech 2021[Feb]; 11 (2): 89 PMID33500874show ga In this paper, we focus on the camelid nanobodies as a revolutionary therapy that can guide efforts to discover new drugs for Coronavirus disease (COVID-19). The small size property makes nanobodies capable of penetrating efficiently into tissues and recognizing cryptic antigens. Strong antigen affinity and stability in the gastrointestinal tract allow them to be used via oral administration. In fact, the use of nanobodies as inhalant can be directly delivered to the target organ, conferring high pulmonary drug concentrations and low systemic drug concentrations and minimal systemic side effects. For that, nanobodies are referred as a class of next-generation antibodies. Nanobodies permit the construction of multivalent formats that may achieve ultra-high neutralization potency and then may prevent mutational escape and can neutralize a wide range of SARS-CoV-2 variants. Due to their distinctive characteristics, nanobodies can be of great use in the development of promising treatment or preventive strategies against SARS-CoV-2 infection. In this review, the state-of-the-art of camel nanobodies design strategies against the virus including SARS-CoV-2 are critically summarized. The application of general nanotechnology was also discussed to mitigate and control emerging SARS-CoV-2 infection. äPerspective on therapeutic and diagnostic potential of camel nanobodie(epmc).pdf DeepDyve Pubget Overpricing