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10.1038/s41598-021-81782-8 http://scihub22266oqcxt.onion/10.1038/s41598-021-81782-8 33500503!7838421!33500503     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2021 ; 11 (1): 2261 Nephropedia Template TP {{tp|p=33500503|t=2021. Overcoming limitations in the availability of swabs systems used for SARS-CoV-2 laboratory diagnostics |pdf=|usr=}}{{33500503}} gab.com Text Overcoming limitations in the availability of swabs systems used for SARS-CoV-2 laboratory diagnostics JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33500503 #FOAvip The diagnosis of COVID-19 relies on the direct detection of SARS-CoV-2 RNA in respiratory specimens by RT-PCR. The pandemic spread of the disease caused an imbalance between demand and supply of materials and reagents needed for diagnostic purposes including swab sets. In a comparative effectiveness study, we conducted serial follow-up swabs in hospitalized laboratory-confirmed COVID-19 patients. We assessed the diagnostic performance of an in-house system developed according to recommendations by the US CDC. In a total of 96 serial swabs, we found significant differences in the accuracy of the different swab systems to generate a positive result in SARS-CoV-2 RT-PCR, ranging from around 50 to 80%. Of note, an in-house swab system was superior to most commercially available sets as reflected by significantly lower Ct values of viral genes. Thus, a simple combination of broadly available materials may enable diagnostic laboratories to bypass global limitations in the supply of swab sets. Twit Text FOAVip Overcoming limitations in the availability of swabs systems used for SARS-CoV-2 laboratory diagnostics ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33500503 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33500503 #FOAvip English Wikipedia <ref>{{Cite pmid|33500503}}</ref> Overcoming limitations in the availability of swabs systems used for SARS-CoV-2 laboratory diagnostics #MMPMID33500503 Nairz M; Bellmann-Weiler R; Ladstatter M; Schullner F; Zimmermann M; Koller AM; Blunder S; Naschberger H; Klotz W; Herold M; Kerndler S; Jeske M; Haschka D; Petzer V; Schroll A; Sonnweber T; Tancevski I; Fritsche G; de Araujo MEG; Stasyk T; Huber LA; Griesmacher A; Theurl I; Weiss G Sci Rep 2021[Jan]; 11 (1): 2261 PMID33500503show ga The diagnosis of COVID-19 relies on the direct detection of SARS-CoV-2 RNA in respiratory specimens by RT-PCR. The pandemic spread of the disease caused an imbalance between demand and supply of materials and reagents needed for diagnostic purposes including swab sets. In a comparative effectiveness study, we conducted serial follow-up swabs in hospitalized laboratory-confirmed COVID-19 patients. We assessed the diagnostic performance of an in-house system developed according to recommendations by the US CDC. In a total of 96 serial swabs, we found significant differences in the accuracy of the different swab systems to generate a positive result in SARS-CoV-2 RT-PCR, ranging from around 50 to 80%. Of note, an in-house swab system was superior to most commercially available sets as reflected by significantly lower Ct values of viral genes. Thus, a simple combination of broadly available materials may enable diagnostic laboratories to bypass global limitations in the supply of swab sets. |COVID-19 Nucleic Acid Testing/*instrumentation/methods[MESH] |COVID-19/*diagnosis[MESH] |Clinical Laboratory Techniques[MESH] |Diagnostic Tests, Routine[MESH] |Disposable Equipment/*supply & distribution[MESH] |Genes, Viral[MESH] |Humans[MESH] |Molecular Diagnostic Techniques/*instrumentation/methods[MESH] |Quality Control[MESH] |RNA, Viral/analysis[MESH] |Reproducibility of Results[MESH] |Resource Allocation[MESH] |SARS-CoV-2/*isolation & purification[MESH]Overcoming limitations in the availability of swabs systems used for S(epmc).pdf DeepDyve Pubget Overpricing