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10.3390/nu13020328 http://scihub22266oqcxt.onion/10.3390/nu13020328 33498631!7911668!33498631     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nutrients 2021 ; 13 (2): ä Nephropedia Template TP {{tp|p=33498631|t=2021. Protective Effects of Lactoferrin against SARS-CoV-2 Infection In Vitro |pdf=|usr=}}{{33498631}} gab.com Text Protective Effects of Lactoferrin against SARS-CoV-2 Infection In Vitro JO: Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=33498631 #FOAvip SARS-CoV-2 is a newly emerging virus that currently lacks curative treatments. Lactoferrin (LF) is a naturally occurring non-toxic glycoprotein with broad-spectrum antiviral, immunomodulatory and anti-inflammatory effects. In this study, we assessed the potential of LF in the prevention of SARS-CoV-2 infection in vitro. Antiviral immune response gene expression was analyzed by qRT-PCR in uninfected Caco-2 intestinal epithelial cells treated with LF. An infection assay for SARS-CoV-2 was performed in Caco-2 cells treated or not with LF. SARS-CoV-2 titer was determined by qRT-PCR, plaque assay and immunostaining. Inflammatory and anti-inflammatory cytokine production was determined by qRT-PCR. LF significantly induced the expression of IFNA1, IFNB1, TLR3, TLR7, IRF3, IRF7 and MAVS genes. Furthermore, LF partially inhibited SARS-CoV-2 infection and replication in Caco-2 intestinal epithelial cells. Our in vitro data support LF as an immune modulator of the antiviral immune response with moderate effects against SARS-CoV-2 infection. Twit Text FOAVip Protective Effects of Lactoferrin against SARS-CoV-2 Infection In Vitro ????Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=33498631 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33498631 #FOAvip English Wikipedia <ref>{{Cite pmid|33498631}}</ref> Protective Effects of Lactoferrin against SARS-CoV-2 Infection In Vitro #MMPMID33498631 Salaris C; Scarpa M; Elli M; Bertolini A; Guglielmetti S; Pregliasco F; Blandizzi C; Brun P; Castagliuolo I Nutrients 2021[Jan]; 13 (2): ä PMID33498631show ga SARS-CoV-2 is a newly emerging virus that currently lacks curative treatments. Lactoferrin (LF) is a naturally occurring non-toxic glycoprotein with broad-spectrum antiviral, immunomodulatory and anti-inflammatory effects. In this study, we assessed the potential of LF in the prevention of SARS-CoV-2 infection in vitro. Antiviral immune response gene expression was analyzed by qRT-PCR in uninfected Caco-2 intestinal epithelial cells treated with LF. An infection assay for SARS-CoV-2 was performed in Caco-2 cells treated or not with LF. SARS-CoV-2 titer was determined by qRT-PCR, plaque assay and immunostaining. Inflammatory and anti-inflammatory cytokine production was determined by qRT-PCR. LF significantly induced the expression of IFNA1, IFNB1, TLR3, TLR7, IRF3, IRF7 and MAVS genes. Furthermore, LF partially inhibited SARS-CoV-2 infection and replication in Caco-2 intestinal epithelial cells. Our in vitro data support LF as an immune modulator of the antiviral immune response with moderate effects against SARS-CoV-2 infection. |*COVID-19/immunology/pathology/prevention & control[MESH] |*Gene Expression Regulation/drug effects/immunology[MESH] |Animals[MESH] |Antiviral Agents/*pharmacology[MESH] |Caco-2 Cells[MESH] |Chlorocebus aethiops[MESH] |Humans[MESH] |Immunity, Innate/*drug effects[MESH] |Lactoferrin/*pharmacology[MESH] |SARS-CoV-2/*immunology[MESH]Protective Effects of Lactoferrin against SARS-CoV-2 Infection In Vitr(epmc).pdf DeepDyve Pubget Overpricing