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10.1007/s00705-020-04947-2

http://scihub22266oqcxt.onion/10.1007/s00705-020-04947-2
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suck abstract from ncbi


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pmid33492525      Arch+Virol 2021 ; 166 (3): 935-941
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  • Replicative capacity of four porcine enteric coronaviruses in LLC-PK1 cells #MMPMID33492525
  • Xiao W; Wang X; Wang J; Fang P; Xiao S; Fang L
  • Arch Virol 2021[Mar]; 166 (3): 935-941 PMID33492525show ga
  • Enteric coronaviruses (CoVs) are major pathogens that cause diarrhea in piglets. To date, four porcine enteric CoVs have been identified: transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and HKU2-like porcine enteric alphacoronavirus (PEAV). In this study, we investigated the replicative capacity of these four enteric CoVs in LLC-PK1 cells, a porcine kidney cell line. The results showed that LLC-PK1 cells are susceptible to all four enteric CoVs, particularly to TGEV and PDCoV infections, indicating that LLC-PK1 cells can be applied to porcine enteric CoV research in vitro, particularly for coinfection studies.
  • |Animals[MESH]
  • |Cell Line[MESH]
  • |Chlorocebus aethiops[MESH]
  • |Deltacoronavirus/*growth & development[MESH]
  • |Disease Susceptibility[MESH]
  • |Fluorescent Antibody Technique, Indirect[MESH]
  • |Gastroenteritis, Transmissible, of Swine/*virology[MESH]
  • |Intestine, Small/virology[MESH]
  • |LLC-PK1 Cells[MESH]
  • |Porcine epidemic diarrhea virus/*growth & development[MESH]
  • |Swine[MESH]
  • |Swine Diseases/virology[MESH]
  • |Transmissible gastroenteritis virus/*growth & development[MESH]
  • |Vero Cells[MESH]


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