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10.1016/j.heliyon.2021.e05951

http://scihub22266oqcxt.onion/10.1016/j.heliyon.2021.e05951
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33490695!7810769!33490695
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suck abstract from ncbi


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pmid33490695      Heliyon 2021 ; 7 (1): e05951
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  • Understanding the implications of SARS-CoV-2 re-infections on immune response milieu, laboratory tests and control measures against COVID-19 #MMPMID33490695
  • Mustapha JO; Abdullahi IN; Ajagbe OOR; Emeribe AU; Fasogbon SA; Onoja SO; Ugwu CE; Umeozuru CM; Ajayi FO; Tanko WN; Omosigho PO; Aliyu AS; Shuwa HA; Nwofe JO; Dangana A; Alaba O; Ghamba PE; Ibrahim Y; Aliyu D; Animasaun OS; Ugboaja NB; Baba Mallam MA; Abubakar SD; Aminu MS; Yahaya H; Oyewusi S
  • Heliyon 2021[Jan]; 7 (1): e05951 PMID33490695show ga
  • Several months after the emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), cases of re-infection after recovery were reported. The extent and duration of protective immunity after SARS-CoV-2 infection is not fully understood. As such, the possibility of re-infection with SARS-CoV-2. Furthermore, cases of re-infection were mainly due to different variants or mutant SARS-CoV-2. Following the fast and pandemic-scale spread of COVID-19, mutations in SARS-CoV-2 have raised new diagnostic challenges which include the redesign of the oligonucleotide sequences used in RT-PCR assays to avoid potential primer-sample mismatches, and decrease sensitivities. Since the initial wave of the pandemic, some regions had experienced fresh outbreaks, predisposing people to be susceptible to SARS-CoV-2 re-infection. Hence, this article sought to offer detailed biology of SARS-CoV-2 re-infections and their implications on immune response milieu, diagnostic laboratory tests and control measures against COVID-19.
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