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10.1007/s12104-020-09996-x

http://scihub22266oqcxt.onion/10.1007/s12104-020-09996-x
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suck abstract from ncbi


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pmid33486617      Biomol+NMR+Assign 2021 ; 15 (1): 137-142
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  • NMR assignments of the macro domain from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) #MMPMID33486617
  • Lin MH; Huang YP; Chang CF; Hsu CH
  • Biomol NMR Assign 2021[Apr]; 15 (1): 137-142 PMID33486617show ga
  • SARS-CoV-2 is a novel pathogen causing pneumonia named COVID-19 and leading to a severe pandemic since the end of 2019. The genome of SARS-CoV-2 contains a macro domain that may play an important role in regulating ADP-ribosylation in host cells and initiating viral replication. Here, we report the (1)H, (13)C, and (15)N resonance assignments of the SARS-CoV-2 macro domain. This work provides the ground for further structural deciphering and biophysical investigation in protein function and antiviral agent design.
  • |*Magnetic Resonance Spectroscopy[MESH]
  • |Carbon Isotopes[MESH]
  • |Genome, Viral[MESH]
  • |Hydrogen[MESH]
  • |Hydrogen-Ion Concentration[MESH]
  • |Nitrogen Isotopes[MESH]
  • |Protein Binding[MESH]
  • |Protein Domains[MESH]
  • |Protein Structure, Secondary[MESH]
  • |SARS-CoV-2/*chemistry[MESH]
  • |Temperature[MESH]
  • |Viral Nonstructural Proteins/*chemistry[MESH]


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