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Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Biomol+NMR+Assign 2021 ; 15 (1): 137-142 Nephropedia Template TP
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NMR assignments of the macro domain from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) #MMPMID33486617
Lin MH; Huang YP; Chang CF; Hsu CH
Biomol NMR Assign 2021[Apr]; 15 (1): 137-142 PMID33486617show ga
SARS-CoV-2 is a novel pathogen causing pneumonia named COVID-19 and leading to a severe pandemic since the end of 2019. The genome of SARS-CoV-2 contains a macro domain that may play an important role in regulating ADP-ribosylation in host cells and initiating viral replication. Here, we report the (1)H, (13)C, and (15)N resonance assignments of the SARS-CoV-2 macro domain. This work provides the ground for further structural deciphering and biophysical investigation in protein function and antiviral agent design.