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10.1016/j.intimp.2020.107364 http://scihub22266oqcxt.onion/10.1016/j.intimp.2020.107364 33486333!7784533!33486333     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+Immunopharmacol 2021 ; 93 (ä): 107364 Nephropedia Template TP {{tp|p=33486333|t=2021. Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview |pdf=|usr=}}{{33486333}} gab.com Text Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview JO: Int Immunopharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33486333 #FOAvip Coronavirus disease 2019 (COVID-19) infection which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to a "public health emergency of international concern" (PHEIC). The infection is highly contagious, has a high mortality rate, and its pathophysiology remains poorly understood. Pulmonary inflammation with substantial lung damage together with generalized immune dysregulation are major components of COVID-19 pathogenesis. The former component, lung damage, seems to be at least in part a consequence of immune dysregulation. Indeed, studies have revealed that immune alteration is not merely an association, as it might occur in systemic infections, but, very likely, the core pathogenic element of COVID-19. In addition, precise management of immune response in COVID-19, i.e. enhancing anti-viral immunity while inhibiting systemic inflammation, may be key to successful treatment. Herein, we have reviewed current evidence related to different aspects of COVID-19 immunology, including innate and adaptive immune responses against the virus and mechanisms of virus-induced immune dysregulation. Considering that current antiviral therapies are chiefly experimental, strategies to do immunotherapy for the management of disease have also been reviewed. Understanding immunology of COVID-19 is important in developing effective therapies as well as diagnostic, and prophylactic strategies for this disease. Twit Text FOAVip Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview ????Int Immunopharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33486333 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33486333 #FOAvip English Wikipedia <ref>{{Cite pmid|33486333}}</ref> Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview #MMPMID33486333 Mohamed Khosroshahi L; Rokni M; Mokhtari T; Noorbakhsh F Int Immunopharmacol 2021[Apr]; 93 (ä): 107364 PMID33486333show ga Coronavirus disease 2019 (COVID-19) infection which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to a "public health emergency of international concern" (PHEIC). The infection is highly contagious, has a high mortality rate, and its pathophysiology remains poorly understood. Pulmonary inflammation with substantial lung damage together with generalized immune dysregulation are major components of COVID-19 pathogenesis. The former component, lung damage, seems to be at least in part a consequence of immune dysregulation. Indeed, studies have revealed that immune alteration is not merely an association, as it might occur in systemic infections, but, very likely, the core pathogenic element of COVID-19. In addition, precise management of immune response in COVID-19, i.e. enhancing anti-viral immunity while inhibiting systemic inflammation, may be key to successful treatment. Herein, we have reviewed current evidence related to different aspects of COVID-19 immunology, including innate and adaptive immune responses against the virus and mechanisms of virus-induced immune dysregulation. Considering that current antiviral therapies are chiefly experimental, strategies to do immunotherapy for the management of disease have also been reviewed. Understanding immunology of COVID-19 is important in developing effective therapies as well as diagnostic, and prophylactic strategies for this disease. |COVID-19/*immunology/pathology/*therapy[MESH] |Humans[MESH] |Immunity[MESH] |Immunotherapy/methods[MESH]Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an (epmc).pdf DeepDyve Pubget Overpricing