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10.1016/j.pdpdt.2021.102184

http://scihub22266oqcxt.onion/10.1016/j.pdpdt.2021.102184
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suck abstract from ncbi


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pmid33484873      Photodiagnosis+Photodyn+Ther 2021 ; 33 (ä): 102184
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  • Effect of intermittent irradiation and fluence-response of 222 nm ultraviolet light on SARS-CoV-2 contamination #MMPMID33484873
  • Kitagawa H; Nomura T; Nazmul T; Kawano R; Omori K; Shigemoto N; Sakaguchi T; Ohge H
  • Photodiagnosis Photodyn Ther 2021[Mar]; 33 (ä): 102184 PMID33484873show ga
  • BACKGROUND: The effectiveness of 222 nm ultraviolet (UV) C light for disinfecting surfaces contaminated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported. The aim of this study was to evaluate the effect of the intermittent irradiation of 222 nm UVC on SARS-CoV-2 and the fluence-dependent effect of 222 nm UVC irradiation on SARS-CoV-2 inactivation. METHODS: We experimented with 5 min continuous and intermittent irradiation for 0.1, 0.05, 0.013, and 0.003 mW/cm(2) of 222 nm UVC to evaluate the differences in the effect of the continuous and intermittent irradiation of 222 nm UVC on SARS-CoV-2 inactivation. For intermittent irradiation, we followed the on-off irradiation cycles with every 10-s irradiation followed by a 380-s interval. Thereafter, we evaluated the effects of 0.1, 0.013, and 0.003 mW/cm(2) 222 nm UVC irradiation on SARS-CoV-2 contamination at UV fluences of 1, 2, and 3 mJ/cm(2) at each irradiance. RESULTS: At each irradiance, no significant difference was observed in the log reduction of SARS-CoV-2 between continuous and intermittent irradiation. At each UV fluence, no significant difference was observed in the log reduction of SARS-CoV-2 among the three different irradiance levels. CONCLUSION: There was no significant difference between continuous and intermittent irradiation with 222 nm UVC with regards to SARS-CoV-2 inactivation. Moreover, 222 nm UVC inactivates SARS-CoV-2 in a fluence-dependent manner. The efficacy of 222-nm UVC irradiation in reducing the contamination of SARS-CoV-2 needs to be further evaluated in a real-world setting.
  • |*Ultraviolet Rays[MESH]
  • |Disinfection/*methods[MESH]
  • |Humans[MESH]
  • |SARS-CoV-2/*radiation effects[MESH]


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