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10.1007/s40620-020-00931-w http://scihub22266oqcxt.onion/10.1007/s40620-020-00931-w 33484426!7823174!33484426     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Nephrol 2021 ; 34 (2): 355-364 Nephropedia Template TP {{tp|p=33484426|t=2021. Proteinuria in COVID-19: prevalence, characterization and prognostic role |pdf=|usr=}}{{33484426}} gab.com Text Proteinuria in COVID-19: prevalence, characterization and prognostic role JO: J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=33484426 #FOAvip BACKGROUND: Proteinuria has been commonly reported in patients with COVID-19. However, only dipstick tests have been frequently used thus far. Here, the quantification and characterization of proteinuria were investigated and their association with mortality was assessed. METHODS: This retrospective, observational, single center study included 153 patients, hospitalized with COVID-19 between March 28th and April 30th, 2020, in whom total proteinuria and urinary alpha(1)-microglobulin (a marker of tubular injury) were measured. Association with mortality was evaluated, with a follow-up until May 7th, 2020. RESULTS: According to the Kidney Disease Improving Global Outcomes staging, 14% (n = 21) of the patients had category 1 proteinuria (< 150 mg/g of urine creatinine), 42% (n = 64) had category 2 (between 150 and 500 mg/g) and 44% (n = 68) had category 3 proteinuria (over 500 mg/g). Urine alpha(1)-microglobulin concentration was higher than 15 mg/g in 89% of patients. After a median follow-up of 27 [14;30] days, the mortality rate reached 18%. Total proteinuria and urinary alpha(1)-microglobulin were associated with mortality in unadjusted and adjusted models. This association was stronger in subgroups of patients with normal renal function and without a urinary catheter. CONCLUSIONS: Proteinuria is frequent in patients with COVID-19. Its characterization suggests a tubular origin, with increased urinary alpha(1)-microglobulin. Tubular proteinuria was associated with mortality in COVID-19 in our restropective, observational study. Twit Text FOAVip Proteinuria in COVID-19: prevalence, characterization and prognostic role ????J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=33484426 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33484426 #FOAvip English Wikipedia <ref>{{Cite pmid|33484426}}</ref> Proteinuria in COVID-19: prevalence, characterization and prognostic role #MMPMID33484426 Huart J; Bouquegneau A; Lutteri L; Erpicum P; Grosch S; Resimont G; Wiesen P; Bovy C; Krzesinski JM; Thys M; Lambermont B; Misset B; Pottel H; Mariat C; Cavalier E; Burtey S; Jouret F; Delanaye P J Nephrol 2021[Apr]; 34 (2): 355-364 PMID33484426show ga BACKGROUND: Proteinuria has been commonly reported in patients with COVID-19. However, only dipstick tests have been frequently used thus far. Here, the quantification and characterization of proteinuria were investigated and their association with mortality was assessed. METHODS: This retrospective, observational, single center study included 153 patients, hospitalized with COVID-19 between March 28th and April 30th, 2020, in whom total proteinuria and urinary alpha(1)-microglobulin (a marker of tubular injury) were measured. Association with mortality was evaluated, with a follow-up until May 7th, 2020. RESULTS: According to the Kidney Disease Improving Global Outcomes staging, 14% (n = 21) of the patients had category 1 proteinuria (< 150 mg/g of urine creatinine), 42% (n = 64) had category 2 (between 150 and 500 mg/g) and 44% (n = 68) had category 3 proteinuria (over 500 mg/g). Urine alpha(1)-microglobulin concentration was higher than 15 mg/g in 89% of patients. After a median follow-up of 27 [14;30] days, the mortality rate reached 18%. Total proteinuria and urinary alpha(1)-microglobulin were associated with mortality in unadjusted and adjusted models. This association was stronger in subgroups of patients with normal renal function and without a urinary catheter. CONCLUSIONS: Proteinuria is frequent in patients with COVID-19. Its characterization suggests a tubular origin, with increased urinary alpha(1)-microglobulin. Tubular proteinuria was associated with mortality in COVID-19 in our restropective, observational study. |Aged[MESH] |Aged, 80 and over[MESH] |Belgium/epidemiology[MESH] |Biomarkers/urine[MESH] |COVID-19/*complications/epidemiology/urine[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Prevalence[MESH] |Prognosis[MESH] |Proteinuria/*epidemiology/etiology/urine[MESH] |Retrospective Studies[MESH]Proteinuria in COVID-19: prevalence, characterization and prognostic r(epmc).pdf DeepDyve Pubget Overpricing