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10.1016/j.addr.2021.01.014

http://scihub22266oqcxt.onion/10.1016/j.addr.2021.01.014
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33482248!7816567!33482248
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suck abstract from ncbi


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pmid33482248      Adv+Drug+Deliv+Rev 2021 ; 172 (ä): 314-338
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  • SARS-CoV-2 vaccines in advanced clinical trials: Where do we stand? #MMPMID33482248
  • Chakraborty S; Mallajosyula V; Tato CM; Tan GS; Wang TT
  • Adv Drug Deliv Rev 2021[May]; 172 (ä): 314-338 PMID33482248show ga
  • The ongoing SARS-CoV-2 pandemic has led to the focused application of resources and scientific expertise toward the goal of developing investigational vaccines to prevent COVID-19. The highly collaborative global efforts by private industry, governments and non-governmental organizations have resulted in a number of SARS-CoV-2 vaccine candidates moving to Phase III trials in a period of only months since the start of the pandemic. In this review, we provide an overview of the preclinical and clinical data on SARS-CoV-2 vaccines that are currently in Phase III clinical trials and in few cases authorized for emergency use. We further discuss relevant vaccine platforms and provide a discussion of SARS-CoV-2 antigens that may be targeted to increase the breadth and durability of vaccine responses.
  • |Animals[MESH]
  • |COVID-19 Vaccines/*administration & dosage/chemistry/immunology[MESH]
  • |COVID-19/epidemiology/immunology/*prevention & control[MESH]
  • |Clinical Trials, Phase III as Topic/*methods[MESH]
  • |Drug Evaluation, Preclinical/methods/trends[MESH]
  • |Humans[MESH]
  • |Protein Structure, Secondary[MESH]
  • |Protein Structure, Tertiary[MESH]


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