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10.1021/acsami.0c19465

http://scihub22266oqcxt.onion/10.1021/acsami.0c19465
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33480246!7857137!33480246
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suck abstract from ncbi


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pmid33480246      ACS+Appl+Mater+Interfaces 2021 ; 13 (5): 5919-5928
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  • Cupric Oxide Coating That Rapidly Reduces Infection by SARS-CoV-2 via Solids #MMPMID33480246
  • Hosseini M; Chin AWH; Behzadinasab S; Poon LLM; Ducker WA
  • ACS Appl Mater Interfaces 2021[Feb]; 13 (5): 5919-5928 PMID33480246show ga
  • The ongoing COVID-19 pandemic has created a need for coatings that reduce infection from SARS-CoV-2 via surfaces. Such a coating could be used on common touch surfaces (e.g., door handles and railings) to reduce both disease transmission and fear of touching objects. Herein, we describe the design, fabrication, and testing of a cupric oxide anti-SARS-CoV-2 coating. Rapid loss of infectivity is an important design criterion, so a porous hydrophilic coating was created to allow rapid infiltration of aqueous solutions into the coating where diffusion distances to the cupric oxide surface are short and the surface area is large. The coating was deposited onto glass from a dispersion of cuprous oxide in ethanol and then thermally treated at 700 degrees C for 2 h to produce a CuO coating that is approximately 30 mum thick. The heat treatment oxidized the cuprous oxide to cupric oxide and sintered the particles into a robust film. The SARS-CoV-2 infectivity from the CuO film was reduced by 99.8% in 30 min and 99.9% in 1 h compared to that from glass. The coating remained hydrophilic for at least 5 months, and there was no significant change in the cross-hatch test of robustness after exposure to 70% ethanol or 3 wt % bleach.
  • |Animals[MESH]
  • |COVID-19/*prevention & control/*virology[MESH]
  • |Chlorocebus aethiops[MESH]
  • |Copper/*pharmacology[MESH]
  • |Humans[MESH]
  • |Photoelectron Spectroscopy[MESH]
  • |SARS-CoV-2/drug effects/*physiology[MESH]
  • |Surface Properties[MESH]
  • |Vero Cells[MESH]
  • |Virus Inactivation/drug effects[MESH]


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