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10.7861/clinmed.2020-0576

http://scihub22266oqcxt.onion/10.7861/clinmed.2020-0576
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33479078!7850226!33479078
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suck abstract from ncbi


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pmid33479078      Clin+Med+(Lond) 2021 ; 21 (1): e14-e19
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  • The prognostic value of chest X-ray in patients with COVID-19 on admission and when starting CPAP #MMPMID33479078
  • Sargent W; Ali S; Kukran S; Harvie M; Soin S
  • Clin Med (Lond) 2021[Jan]; 21 (1): e14-e19 PMID33479078show ga
  • OBJECTIVE: The objective was to explore if chest X-ray severity, assessed using a validated scoring system, predicts patient outcome on admission and when starting continuous positive pressure ventilation (CPAP) for COVID-19. DESIGN: The study was a retrospective case-controlled study. PARTICIPANTS: There were 163 patients with COVID-19 deemed candidates for CPAP on admission, including 58 who subsequently required CPAP. OUTCOME MEASURES: On admission, we measured the proportion of patients meeting a composite 'negative' outcome of requiring CPAP, intubation or dying versus successful ward-based care. For those escalated to CPAP, 'negative' outcomes were intubation or death versus successful de-escalation of respiratory support. RESULTS: Our results were stratified into tertiles, those with 'moderate' or 'severe' X-rays on admission had significantly higher odds of negative outcome versus 'mild' (odds ratio (OR) 2.32; 95% confidence interval (CI) 1.121-4.803; p=0.023; and OR 3.600; 95% CI 1.681-7.708; p=0.001, respectively). This could not be demonstrated in those commencing CPAP (OR 0.976; 95% CI 0.754-1.264; p=0.856). CONCLUSIONS: We outline a scoring system to stratify X-rays by severity and directly link this to prognosis. However, we were unable to demonstrate this association in the patients commencing CPAP.
  • |*Pandemics[MESH]
  • |*Patient Admission[MESH]
  • |*SARS-CoV-2[MESH]
  • |COVID-19/*diagnosis/epidemiology/therapy[MESH]
  • |Case-Control Studies[MESH]
  • |Continuous Positive Airway Pressure/*methods[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Radiography, Thoracic/*methods[MESH]


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