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Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Clin+Med+(Lond) 2021 ; 21 (1): 79-80 Nephropedia Template TP
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Lesson of the month: Severe granulomatosis with polyangiitis (GPA): a diagnostic challenge during the COVID-19 pandemic #MMPMID33479073
Qurratulain Q; Ahmed A; Jones Q
Clin Med (Lond) 2021[Jan]; 21 (1): 79-80 PMID33479073show ga
We present the case of a 71-year-old woman with bilateral pneumonia who continued to deteriorate despite multiple courses of antibiotics. When dexamethasone was added to cover the possibility of COVID-19 pneumonia, she rapidly improved. Subsequently, she was found to have a strongly positive PR3 anti-nuclear cytoplasmic antibody (ANCA) and clinical features consistent with granulomatosis with polyangiitis (GPA) with upper respiratory tract and renal involvement. The case highlights how the COVID-19 pandemic can create new challenges in the diagnosis of GPA.
|*SARS-CoV-2[MESH]
|Aged[MESH]
|COVID-19/diagnosis/*epidemiology[MESH]
|Comorbidity[MESH]
|Diagnosis, Differential[MESH]
|Female[MESH]
|Granulomatosis with Polyangiitis/*diagnosis/epidemiology[MESH]