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10.1186/s13040-021-00234-1 http://scihub22266oqcxt.onion/10.1186/s13040-021-00234-1 33478554!7817765!33478554     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33478554&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\33478554.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BioData+Min 2021 ; 14 (1): 5 Nephropedia Template TP {{tp|p=33478554|t=2021. Mechanistic modeling of the SARS-CoV-2 disease map |pdf=|usr=}}{{33478554}} gab.com Text Mechanistic modeling of the SARS-CoV-2 disease map JO: BioData Min http://www.kidney.de/pget.php?&tw=1&pmid=33478554 #FOAvip Here we present a web interface that implements a comprehensive mechanistic model of the SARS-CoV-2 disease map. In this framework, the detailed activity of the human signaling circuits related to the viral infection, covering from the entry and replication mechanisms to the downstream consequences as inflammation and antigenic response, can be inferred from gene expression experiments. Moreover, the effect of potential interventions, such as knock-downs, or drug effects (currently the system models the effect of more than 8000 DrugBank drugs) can be studied. This freely available tool not only provides an unprecedentedly detailed view of the mechanisms of viral invasion and the consequences in the cell but has also the potential of becoming an invaluable asset in the search for efficient antiviral treatments. Twit Text FOAVip Mechanistic modeling of the SARS-CoV-2 disease map ????BioData Min http://www.kidney.de/pget.php?&tw=1&pmid=33478554 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33478554 #FOAvip English Wikipedia <ref>{{Cite pmid|33478554}}</ref> Mechanistic modeling of the SARS-CoV-2 disease map #MMPMID33478554 Rian K; Esteban-Medina M; Hidalgo MR; Cubuk C; Falco MM; Loucera C; Gunyel D; Ostaszewski M; Pena-Chilet M; Dopazo J BioData Min 2021[Jan]; 14 (1): 5 PMID33478554show ga Here we present a web interface that implements a comprehensive mechanistic model of the SARS-CoV-2 disease map. In this framework, the detailed activity of the human signaling circuits related to the viral infection, covering from the entry and replication mechanisms to the downstream consequences as inflammation and antigenic response, can be inferred from gene expression experiments. Moreover, the effect of potential interventions, such as knock-downs, or drug effects (currently the system models the effect of more than 8000 DrugBank drugs) can be studied. This freely available tool not only provides an unprecedentedly detailed view of the mechanisms of viral invasion and the consequences in the cell but has also the potential of becoming an invaluable asset in the search for efficient antiviral treatments. äMechanistic modeling of the SARS-CoV-2 disease map (epmc).pdf DeepDyve Pubget Overpricing