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10.1016/j.meegid.2021.104724 http://scihub22266oqcxt.onion/10.1016/j.meegid.2021.104724 33476804!7816605!33476804     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Infect+Genet+Evol 2021 ; 89 (ä): 104724 Nephropedia Template TP {{tp|p=33476804|t=2021. Clade GR and clade GH isolates of SARS-CoV-2 in Asia show highest amount of SNPs |pdf=|usr=}}{{33476804}} gab.com Text Clade GR and clade GH isolates of SARS-CoV-2 in Asia show highest amount of SNPs JO: Infect Genet Evol http://www.kidney.de/pget.php?&tw=1&pmid=33476804 #FOAvip Clades are monophyletic groups composed of a common ancestor and all its lineal descendants. As the propensity of virulence of a disease depends upon the type of clade the virus belongs to and it causes different fatality rates of disease in different countries, so the clade-wise analysis of SARS-CoV-2 isolates collected from different countries can illuminate the actual evolutionary relationships between them. In this study, 1566 SARS-CoV-2 genome sequences across ten Asian countries are collected, clustered, and characterized based on the clade they belong to. The isolates are compared to the Wuhan reference sequence" hCoV-19/Wuhan/WIV04/19'' to identify the mutations that occurred at different protein regions. Structural changes in amino acids due to mutations lead to functional instability of the proteins. Detailed clade-wise functional assessments are carried out to quantify the stability and vulnerability of the mutations occurring in SARS-CoV-2 genomes which can shade light on personalized prevention and treatment of the disease and encourage towards the invention of clade-specific vaccines. Twit Text FOAVip Clade GR and clade GH isolates of SARS-CoV-2 in Asia show highest amount of SNPs ????Infect Genet Evol http://www.kidney.de/pget.php?&tw=1&pmid=33476804 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33476804 #FOAvip English Wikipedia <ref>{{Cite pmid|33476804}}</ref> Clade GR and clade GH isolates of SARS-CoV-2 in Asia show highest amount of SNPs #MMPMID33476804 Sengupta A; Hassan SS; Choudhury PP Infect Genet Evol 2021[Apr]; 89 (ä): 104724 PMID33476804show ga Clades are monophyletic groups composed of a common ancestor and all its lineal descendants. As the propensity of virulence of a disease depends upon the type of clade the virus belongs to and it causes different fatality rates of disease in different countries, so the clade-wise analysis of SARS-CoV-2 isolates collected from different countries can illuminate the actual evolutionary relationships between them. In this study, 1566 SARS-CoV-2 genome sequences across ten Asian countries are collected, clustered, and characterized based on the clade they belong to. The isolates are compared to the Wuhan reference sequence" hCoV-19/Wuhan/WIV04/19'' to identify the mutations that occurred at different protein regions. Structural changes in amino acids due to mutations lead to functional instability of the proteins. Detailed clade-wise functional assessments are carried out to quantify the stability and vulnerability of the mutations occurring in SARS-CoV-2 genomes which can shade light on personalized prevention and treatment of the disease and encourage towards the invention of clade-specific vaccines. |*Polymorphism, Single Nucleotide[MESH] |Asia[MESH] |Mutation[MESH] |Phylogeny[MESH]Clade GR and clade GH isolates of SARS-CoV-2 in Asia show highest amou(epmc).pdf DeepDyve Pubget Overpricing