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10.1016/j.ccell.2021.01.001 http://scihub22266oqcxt.onion/10.1016/j.ccell.2021.01.001 33476581!7833668!33476581     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancer+Cell 2021 ; 39 (2): 257-275.e6 Nephropedia Template TP {{tp|p=33476581|t=2021. Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients |pdf=|usr=}}{{33476581}} gab.com Text Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients JO: Cancer Cell http://www.kidney.de/pget.php?&tw=1&pmid=33476581 #FOAvip Given the immune system's importance for cancer surveillance and treatment, we have investigated how it may be affected by SARS-CoV-2 infection of cancer patients. Across some heterogeneity in tumor type, stage, and treatment, virus-exposed solid cancer patients display a dominant impact of SARS-CoV-2, apparent from the resemblance of their immune signatures to those for COVID-19(+) non-cancer patients. This is not the case for hematological malignancies, with virus-exposed patients collectively displaying heterogeneous humoral responses, an exhausted T cell phenotype and a high prevalence of prolonged virus shedding. Furthermore, while recovered solid cancer patients' immunophenotypes resemble those of non-virus-exposed cancer patients, recovered hematological cancer patients display distinct, lingering immunological legacies. Thus, while solid cancer patients, including those with advanced disease, seem no more at risk of SARS-CoV-2-associated immune dysregulation than the general population, hematological cancer patients show complex immunological consequences of SARS-CoV-2 exposure that might usefully inform their care. Twit Text FOAVip Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients ????Cancer Cell http://www.kidney.de/pget.php?&tw=1&pmid=33476581 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33476581 #FOAvip English Wikipedia <ref>{{Cite pmid|33476581}}</ref> Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients #MMPMID33476581 Abdul-Jawad S; Bau L; Alaguthurai T; Del Molino Del Barrio I; Laing AG; Hayday TS; Monin L; Munoz-Ruiz M; McDonald L; Francos Quijorna I; McKenzie D; Davis R; Lorenc A; Chan JNE; Ryan S; Bugallo-Blanco E; Yorke R; Kamdar S; Fish M; Zlatareva I; Vantourout P; Jennings A; Gee S; Doores K; Bailey K; Hazell S; De Naurois J; Moss C; Russell B; Khan AA; Rowley M; Benjamin R; Enting D; Alrifai D; Wu Y; Zhou Y; Barber P; Ng T; Spicer J; Van Hemelrijck M; Kumar M; Vidler J; Lwin Y; Fields P; Karagiannis SN; Coolen ACC; Rigg A; Papa S; Hayday AC; Patten PEM; Irshad S Cancer Cell 2021[Feb]; 39 (2): 257-275.e6 PMID33476581show ga Given the immune system's importance for cancer surveillance and treatment, we have investigated how it may be affected by SARS-CoV-2 infection of cancer patients. Across some heterogeneity in tumor type, stage, and treatment, virus-exposed solid cancer patients display a dominant impact of SARS-CoV-2, apparent from the resemblance of their immune signatures to those for COVID-19(+) non-cancer patients. This is not the case for hematological malignancies, with virus-exposed patients collectively displaying heterogeneous humoral responses, an exhausted T cell phenotype and a high prevalence of prolonged virus shedding. Furthermore, while recovered solid cancer patients' immunophenotypes resemble those of non-virus-exposed cancer patients, recovered hematological cancer patients display distinct, lingering immunological legacies. Thus, while solid cancer patients, including those with advanced disease, seem no more at risk of SARS-CoV-2-associated immune dysregulation than the general population, hematological cancer patients show complex immunological consequences of SARS-CoV-2 exposure that might usefully inform their care. |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |COVID-19/etiology/*immunology/mortality[MESH] |Female[MESH] |Hematologic Neoplasms/immunology/mortality/therapy/virology[MESH] |Humans[MESH] |Immunophenotyping[MESH] |Male[MESH] |Middle Aged[MESH] |Nasopharynx/virology[MESH] |Neoplasms/*immunology/mortality/therapy/*virology[MESH] |Severe Acute Respiratory Syndrome/etiology/*immunology/mortality/virology[MESH] |T-Lymphocytes/virology[MESH] |Virus Shedding[MESH]Acute Immune Signatures and Their Legacies in Severe Acute Respiratory(epmc).pdf DeepDyve Pubget Overpricing