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10.1002/jmv.26814 http://scihub22266oqcxt.onion/10.1002/jmv.26814 33475167!8014870!33475167     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Med+Virol 2021 ; 93 (5): 2722-2734 Nephropedia Template TP {{tp|p=33475167|t=2021. Targeting SARS-CoV-2 viral proteases as a therapeutic strategy to treat COVID-19 |pdf=|usr=}}{{33475167}} gab.com Text Targeting SARS-CoV-2 viral proteases as a therapeutic strategy to treat COVID-19 JO: J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=33475167 #FOAvip The 21st century has witnessed three outbreaks of coronavirus (CoVs) infections caused by severe acute respiratory syndrome (SARS)-CoV, Middle East respiratory syndrome (MERS)-CoV, and SARS-CoV-2. Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, spreads rapidly and since the discovery of the first COVID-19 infection in December 2019, has caused 1.2 million deaths worldwide and 226,777 deaths in the United States alone. The high amino acid similarity between SARS-CoV and SARS-CoV-2 viral proteins supports testing therapeutic molecules that were designed to treat SARS infections during the 2003 epidemic. In this review, we provide information on possible COVID-19 treatment strategies that act via inhibition of the two essential proteins of the virus, 3C-like protease (3CL(pro) ) or papain-like protease (PL(pro) ). Twit Text FOAVip Targeting SARS-CoV-2 viral proteases as a therapeutic strategy to treat COVID-19 ????J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=33475167 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33475167 #FOAvip English Wikipedia <ref>{{Cite pmid|33475167}}</ref> Targeting SARS-CoV-2 viral proteases as a therapeutic strategy to treat COVID-19 #MMPMID33475167 Anirudhan V; Lee H; Cheng H; Cooper L; Rong L J Med Virol 2021[May]; 93 (5): 2722-2734 PMID33475167show ga The 21st century has witnessed three outbreaks of coronavirus (CoVs) infections caused by severe acute respiratory syndrome (SARS)-CoV, Middle East respiratory syndrome (MERS)-CoV, and SARS-CoV-2. Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, spreads rapidly and since the discovery of the first COVID-19 infection in December 2019, has caused 1.2 million deaths worldwide and 226,777 deaths in the United States alone. The high amino acid similarity between SARS-CoV and SARS-CoV-2 viral proteins supports testing therapeutic molecules that were designed to treat SARS infections during the 2003 epidemic. In this review, we provide information on possible COVID-19 treatment strategies that act via inhibition of the two essential proteins of the virus, 3C-like protease (3CL(pro) ) or papain-like protease (PL(pro) ). |*COVID-19 Drug Treatment[MESH] |Antiviral Agents/*therapeutic use[MESH] |COVID-19/epidemiology[MESH] |Coronavirus 3C Proteases/chemistry/drug effects/genetics[MESH] |Coronavirus Papain-Like Proteases/chemistry/drug effects/genetics[MESH] |Humans[MESH] |Middle East Respiratory Syndrome Coronavirus[MESH] |Protease Inhibitors/therapeutic use[MESH] |SARS-CoV-2/genetics/metabolism[MESH] |Viral Nonstructural Proteins/chemistry/genetics[MESH]Targeting SARS-CoV-2 viral proteases as a therapeutic strategy to trea(epmc).pdf DeepDyve Pubget Overpricing