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10.1007/s00431-021-03955-x

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suck abstract from ncbi


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pmid33474580      Eur+J+Pediatr 2021 ; 180 (5): 1659-1663
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  • Demographic predictors of hospitalization and mortality in US children with COVID-19 #MMPMID33474580
  • Moreira A; Chorath K; Rajasekaran K; Burmeister F; Ahmed M; Moreira A
  • Eur J Pediatr 2021[May]; 180 (5): 1659-1663 PMID33474580show ga
  • Understanding which children are at increased risk for poor outcome with COVID-19 is critical. In this study, we link pediatric population-based data from the US Center for Disease Control and Prevention to COVID-19 hospitalization and in-hospital death. In 27,045 US children with confirmed COVID-19, we demonstrate that African American [OR 2.28 (95% CI: 1.93, 2.70)] or mixed race [OR 2.95 (95% CI: 2.28, 3.82)] and an underlying medical condition [OR 3.55 (95% CI: 3.14, 4.01)] are strong predictors for hospitalization. Death occurred in 39 (0.19%) of 20,096 hospitalized children; children with a prior medical condition had an increased odd for death [OR 8.8 (95% CI: 3.7, 21.1)].Conclusion: Hospitalization and in-hospital death are rare in children diagnosed with COVID-19. However, children at higher risk for these outcomes include those with an underlying medical condition, as well as those of African American descent. What is Known: * Demographic factors are independent prognosticators of poor outcome in children with COVID-19. What is New: * Children with an underlying medical condition and those from an African American or mixed race/ethnicity are at high risk for COVID-19 hospitalization. * History of a comorbidity supersedes age, gender, and race/ethnicity as a risk factor for in-hospital pediatric COVID-19 death.
  • |*Hospital Mortality[MESH]
  • |Adolescent[MESH]
  • |COVID-19/*mortality[MESH]
  • |Child[MESH]
  • |Child, Hospitalized[MESH]
  • |Child, Preschool[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Infant, Newborn[MESH]
  • |Male[MESH]
  • |United States/epidemiology[MESH]


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