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10.3390/pathogens10010038

http://scihub22266oqcxt.onion/10.3390/pathogens10010038
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33466537!7824818!33466537
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suck abstract from ncbi


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pmid33466537      Pathogens 2021 ; 10 (1): ä
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  • Limits and Opportunities of SARS-CoV-2 Antigen Rapid Tests: An Experienced-Based Perspective #MMPMID33466537
  • Schildgen V; Demuth S; Lusebrink J; Schildgen O
  • Pathogens 2021[Jan]; 10 (1): ä PMID33466537show ga
  • BACKGROUND: Due to the steadily rising case numbers of SARS-CoV-2 infections worldwide, there is an increasing need for reliable rapid diagnostic devices in addition to existing gold standard PCR methods. Actually, public attention is focused on antigen assays including lateral flow tests (LFTs) as a diagnostic alternative. Therefore, different LFTs were analyzed regarding their performance in a clinical setting. MATERIAL AND METHODS: A pilot sample panel of 13 bronchoalveolar fluids (BALFs) and 60 throat washing (TW) samples with confirmed PCR results, as well as eight throat washes invalid by PCR, were tested with the BIOCREDIT test (RapiGEN), the Panbio(TM) assay (Abbott), and the SARS-CoV-2 rapid antigen test (Roche). CONCLUSION: The analyzed antigen test showed an interassay correlation of 27.4%, with overall specificities ranging from 19.4% to 87.1%, while sensitivities of the respective tests ranged between 33.3% and 88.1%. Because these assays did not entirely meet all high expectations, their benefit has to be carefully evaluated for the respective test strategy and setting.
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