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10.1007/s00705-021-04958-7 http://scihub22266oqcxt.onion/10.1007/s00705-021-04958-7 33462671!7812983!33462671     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Arch+Virol 2021 ; 166 (3): 675-696 Nephropedia Template TP {{tp|p=33462671|t=2021. The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV |pdf=|usr=}}{{33462671}} gab.com Text The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV JO: Arch Virol http://www.kidney.de/pget.php?&tw=1&pmid=33462671 #FOAvip The number of descriptions of emerging viruses has grown at an unprecedented rate since the beginning of the 21(st) century. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is the third highly pathogenic coronavirus that has introduced itself into the human population in the current era, after SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV). Molecular and cellular studies of the pathogenesis of this novel coronavirus are still in the early stages of research; however, based on similarities of SARS-CoV-2 to other coronaviruses, it can be hypothesized that the NF-kappaB, cytokine regulation, ERK, and TNF-alpha signaling pathways are the likely causes of inflammation at the onset of COVID-19. Several drugs have been prescribed and used to alleviate the adverse effects of these inflammatory cellular signaling pathways, and these might be beneficial for developing novel therapeutic modalities against COVID-19. In this review, we briefly summarize alterations of cellular signaling pathways that are associated with coronavirus infection, particularly SARS-CoV and MERS-CoV, and tabulate the therapeutic agents that are currently approved for treating other human diseases. Twit Text FOAVip The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV ????Arch Virol http://www.kidney.de/pget.php?&tw=1&pmid=33462671 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33462671 #FOAvip English Wikipedia <ref>{{Cite pmid|33462671}}</ref> The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV #MMPMID33462671 Hemmat N; Asadzadeh Z; Ahangar NK; Alemohammad H; Najafzadeh B; Derakhshani A; Baghbanzadeh A; Baghi HB; Javadrashid D; Najafi S; Ar Gouilh M; Baradaran B Arch Virol 2021[Mar]; 166 (3): 675-696 PMID33462671show ga The number of descriptions of emerging viruses has grown at an unprecedented rate since the beginning of the 21(st) century. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is the third highly pathogenic coronavirus that has introduced itself into the human population in the current era, after SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV). Molecular and cellular studies of the pathogenesis of this novel coronavirus are still in the early stages of research; however, based on similarities of SARS-CoV-2 to other coronaviruses, it can be hypothesized that the NF-kappaB, cytokine regulation, ERK, and TNF-alpha signaling pathways are the likely causes of inflammation at the onset of COVID-19. Several drugs have been prescribed and used to alleviate the adverse effects of these inflammatory cellular signaling pathways, and these might be beneficial for developing novel therapeutic modalities against COVID-19. In this review, we briefly summarize alterations of cellular signaling pathways that are associated with coronavirus infection, particularly SARS-CoV and MERS-CoV, and tabulate the therapeutic agents that are currently approved for treating other human diseases. |COVID-19 Drug Treatment[MESH] |COVID-19/*pathology[MESH] |Cytokines/metabolism[MESH] |Extracellular Signal-Regulated MAP Kinases/metabolism[MESH] |Humans[MESH] |Inflammation/pathology[MESH] |Middle East Respiratory Syndrome Coronavirus/drug effects/*metabolism[MESH] |NF-kappa B/metabolism[MESH] |SARS-CoV-2/drug effects/*metabolism[MESH] |Signal Transduction/*physiology[MESH]The roles of signaling pathways in SARS-CoV-2 infection; lessons learn(epmc).pdf DeepDyve Pubget Overpricing