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10.1136/bcr-2020-239782

http://scihub22266oqcxt.onion/10.1136/bcr-2020-239782
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33462059!7813411!33462059
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suck abstract from ncbi


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pmid33462059      BMJ+Case+Rep 2021 ; 14 (1): ä
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  • Severe acute mitral valve regurgitation in a COVID-19-infected patient #MMPMID33462059
  • Khanduri A; Anand U; Doss M; Lovett L
  • BMJ Case Rep 2021[Jan]; 14 (1): ä PMID33462059show ga
  • The ongoing SARS-CoV-2 (COVID-19) pandemic has presented many difficult and unique challenges to the medical community. We describe a case of a middle-aged COVID-19-positive man who presented with pulmonary oedema and acute respiratory failure. He was initially diagnosed with acute respiratory distress syndrome. Later in the hospital course, his pulmonary oedema and respiratory failure worsened as result of severe acute mitral valve regurgitation secondary to direct valvular damage from COVID-19 infection. The patient underwent emergent surgical mitral valve replacement. Pathological evaluation of the damaged valve was confirmed to be secondary to COVID-19 infection. The histopathological findings were consistent with prior cardiopulmonary autopsy sections of patients with COVID-19 described in the literature as well as proposed theories regarding ACE2 receptor activity. This case highlights the potential of SARS-CoV-2 causing direct mitral valve damage resulting in severe mitral valve insufficiency with subsequent pulmonary oedema and respiratory failure.
  • |Acute Disease[MESH]
  • |Atrial Fibrillation/complications/physiopathology[MESH]
  • |COVID-19/*complications/therapy[MESH]
  • |Chordae Tendineae/diagnostic imaging[MESH]
  • |Echocardiography[MESH]
  • |Electrocardiography[MESH]
  • |Heart Valve Prosthesis Implantation[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Mitral Valve Insufficiency/diagnostic imaging/*etiology/physiopathology/surgery[MESH]
  • |Pulmonary Edema/etiology/physiopathology/therapy[MESH]
  • |Respiratory Insufficiency/etiology/physiopathology/therapy[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]


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