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10.1136/bcr-2020-238716

http://scihub22266oqcxt.onion/10.1136/bcr-2020-238716
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33462030!7813301!33462030
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suck abstract from ncbi


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pmid33462030      BMJ+Case+Rep 2021 ; 14 (1): ä
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  • Fulminant Bacillus cereus food poisoning with fatal multi-organ failure #MMPMID33462030
  • Colaco CMG; Basile K; Draper J; Ferguson PE
  • BMJ Case Rep 2021[Jan]; 14 (1): ä PMID33462030show ga
  • This case represents a rare fulminant course of fried-rice associated food poisoning in an immunocompetent person due to pre-formed exotoxin produced by Bacillus cereus, with severe manifestations of sepsis, including multi-organ (hepatic, renal, cardiac, respiratory and neurological) failure, shock, metabolic acidosis, rhabdomyolysis and coagulopathy. Despite maximal supportive measures (continuous renal replacement therapy, plasmapheresis, N-acetylcysteine infusion and blood products, and broad-spectrum antimicrobials) and input from a multidisciplinary team (consisting of infectious diseases, intensive care, gastroenterology, surgery, toxicology, immunology and haematology), mortality resulted. This case is the first to use whole genome sequencing techniques to confirm the toxigenic potential of B. cereus It has important implications for food preparation and storage, particularly given its occurrence in home isolation during the COVID-19 pandemic.
  • |Acetylcysteine/therapeutic use[MESH]
  • |Acidosis/physiopathology/therapy[MESH]
  • |Adult[MESH]
  • |Anti-Arrhythmia Agents/therapeutic use[MESH]
  • |Anti-Bacterial Agents/therapeutic use[MESH]
  • |Arrhythmias, Cardiac/physiopathology/therapy[MESH]
  • |Bacillus cereus/*genetics/isolation & purification[MESH]
  • |Blood Coagulation Disorders/physiopathology/therapy[MESH]
  • |Blood Transfusion[MESH]
  • |Brain Diseases[MESH]
  • |Continuous Renal Replacement Therapy[MESH]
  • |Exotoxins/*genetics[MESH]
  • |Fatal Outcome[MESH]
  • |Female[MESH]
  • |Foodborne Diseases/*diagnosis/microbiology/physiopathology/therapy[MESH]
  • |Free Radical Scavengers/therapeutic use[MESH]
  • |Humans[MESH]
  • |Immunocompetence[MESH]
  • |Liver Failure/physiopathology/therapy[MESH]
  • |Multiple Organ Failure/physiopathology/therapy[MESH]
  • |Plasmapheresis[MESH]
  • |Renal Insufficiency/physiopathology/therapy[MESH]
  • |Rhabdomyolysis/physiopathology/therapy[MESH]
  • |Sepsis/physiopathology/therapy[MESH]
  • |Shock/physiopathology[MESH]
  • |Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization[MESH]


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