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10.1016/j.aca.2020.10.009 http://scihub22266oqcxt.onion/10.1016/j.aca.2020.10.009 33461715!7548029!33461715     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Anal+Chim+Acta 2021 ; 1146 (ä): 184-199 Nephropedia Template TP {{tp|p=33461715|t=2021. A critical review of point-of-care diagnostic technologies to combat viral pandemics |pdf=|usr=}}{{33461715}} gab.com Text A critical review of point-of-care diagnostic technologies to combat viral pandemics JO: Anal Chim Acta http://www.kidney.de/pget.php?&tw=1&pmid=33461715 #FOAvip The COVID-19 global pandemic of 2019-2020 pointedly revealed the lack of diagnostic solutions that are able to keep pace with the rapid spread of the virus. Despite the promise of decades of lab-on-a-chip research, no commercial products were available to deliver rapid results or enable testing in the field at the onset of the pandemic. In this critical review, we assess the current state of progress on the development of point-of-care technologies for the diagnosis of viral diseases that cause pandemics. While many previous reviews have reported on progress in various lab-on-a-chip technologies, here we address the literature from the perspective of the testing needs of a rapidly expanding pandemic. First, we recommend a set of requirements to heed when designing point-of-care diagnostic technologies to address the testing needs of a pandemic. We then review the current state of assay technologies with a focus on isothermal amplification and lateral-flow immunoassays. Though there is much progress on assay development, we argue that the largest roadblock to deployment exists in sample preparation. We summarize current approaches to automate sample preparation and discuss both the progress and shortcomings of these developments. Finally, we provide our recommendations to the field of specific challenges to address in order to prepare for the next pandemic. Twit Text FOAVip A critical review of point-of-care diagnostic technologies to combat viral pandemics ????Anal Chim Acta http://www.kidney.de/pget.php?&tw=1&pmid=33461715 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33461715 #FOAvip English Wikipedia <ref>{{Cite pmid|33461715}}</ref> A critical review of point-of-care diagnostic technologies to combat viral pandemics #MMPMID33461715 Everitt ML; Tillery A; David MG; Singh N; Borison A; White IM Anal Chim Acta 2021[Feb]; 1146 (ä): 184-199 PMID33461715show ga The COVID-19 global pandemic of 2019-2020 pointedly revealed the lack of diagnostic solutions that are able to keep pace with the rapid spread of the virus. Despite the promise of decades of lab-on-a-chip research, no commercial products were available to deliver rapid results or enable testing in the field at the onset of the pandemic. In this critical review, we assess the current state of progress on the development of point-of-care technologies for the diagnosis of viral diseases that cause pandemics. While many previous reviews have reported on progress in various lab-on-a-chip technologies, here we address the literature from the perspective of the testing needs of a rapidly expanding pandemic. First, we recommend a set of requirements to heed when designing point-of-care diagnostic technologies to address the testing needs of a pandemic. We then review the current state of assay technologies with a focus on isothermal amplification and lateral-flow immunoassays. Though there is much progress on assay development, we argue that the largest roadblock to deployment exists in sample preparation. We summarize current approaches to automate sample preparation and discuss both the progress and shortcomings of these developments. Finally, we provide our recommendations to the field of specific challenges to address in order to prepare for the next pandemic. |*Pandemics[MESH] |COVID-19/*diagnosis[MESH] |Humans[MESH] |Lab-On-A-Chip Devices[MESH] |Point-of-Care Systems/*trends[MESH]A critical review of point-of-care diagnostic technologies to combat v(epmc).pdf DeepDyve Pubget Overpricing