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10.1080/10428194.2021.1872070

http://scihub22266oqcxt.onion/10.1080/10428194.2021.1872070
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33461387!7832449!33461387
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suck abstract from ncbi


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pmid33461387      Leuk+Lymphoma 2021 ; 62 (6): 1490-1496
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  • Convalescent hyperimmune plasma for chemo-immunotherapy induced immunodeficiency in COVID-19 patients with hematological malignancies #MMPMID33461387
  • Ferrari S; Caprioli C; Weber A; Rambaldi A; Lussana F
  • Leuk Lymphoma 2021[Jun]; 62 (6): 1490-1496 PMID33461387show ga
  • During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak, patients with defective immunity after chemo-immunotherapy due to hematological disorders showed prolonged symptoms and worse prognosis of coronavirus disease-2019 (COVID-19) pneumonia, probably due to inadequate adaptive immune response and noneffective viral clearance. We describe a single-center series of hematological immunocompromised patients undergoing passive immunization with hyperimmune plasma for persistent COVID-19 symptoms. In all cases, such treatment was well tolerated and contributed to clinical and radiological improvement and recovery; viral clearance was also achieved in a patients' subset. Although requiring further investigation, these results suggest a specific role for hyperimmune plasma administration in hematological patients.
  • |*COVID-19[MESH]
  • |*Hematologic Neoplasms/complications/diagnosis/therapy[MESH]
  • |*Immunologic Deficiency Syndromes[MESH]
  • |Humans[MESH]
  • |Immunization, Passive[MESH]


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