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10.1016/j.tem.2021.01.001

http://scihub22266oqcxt.onion/10.1016/j.tem.2021.01.001
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33455862!7833986!33455862
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suck abstract from ncbi


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pmid33455862      Trends+Endocrinol+Metab 2021 ; 32 (3): 132-134
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  • Altered Cholesterol and Lipid Synthesis Mediates Hyperinflammation in COVID-19 #MMPMID33455862
  • Sohrabi Y; Reinecke H; Godfrey R
  • Trends Endocrinol Metab 2021[Mar]; 32 (3): 132-134 PMID33455862show ga
  • Recent data have revealed that fructose-rich diet triggers inflammation and lipid synthesis. Furthermore, lipid metabolism, cholesterol synthesis and sterol regulatory element binding protein-2 (SREBP-2) activation correlates with coronavirus disease 2019 (COVID-19)-induced cytokine storm. High fructose consumption result in SREBPs activation, altered cholesterol and lipid synthesis and may establish an innate immune memory in the cells, leading to severe COVID-19 in patients with obesity.
  • |*COVID-19[MESH]
  • |*Lipogenesis[MESH]
  • |CCAAT-Enhancer-Binding Proteins/metabolism[MESH]
  • |Cholesterol[MESH]
  • |Fructose[MESH]
  • |Humans[MESH]
  • |Inflammation[MESH]
  • |SARS-CoV-2[MESH]


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