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10.1016/j.jconrel.2021.01.017 http://scihub22266oqcxt.onion/10.1016/j.jconrel.2021.01.017 33450319!7803629!33450319     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Control+Release 2021 ; 331 (ä): 30-44 Nephropedia Template TP {{tp|p=33450319|t=2021. Development of nanoparticle-delivery systems for antiviral agents: A review |pdf=|usr=}}{{33450319}} gab.com Text Development of nanoparticle-delivery systems for antiviral agents: A review JO: J Control Release http://www.kidney.de/pget.php?&tw=1&pmid=33450319 #FOAvip The COVID-19 pandemic has resulted in unprecedented increases in sickness, death, economic disruption, and social disturbances globally. However, the virus (SARS-CoV-2) that caused this pandemic is only one of many viruses threatening public health. Consequently, it is important to have effective means of preventing viral transmission and reducing its devastating effects on human and animal health. Although many antivirals are already available, their efficacy is often limited because of factors such as poor solubility, low permeability, poor bioavailability, un-targeted release, adverse side effects, and antiviral resistance. Many of these problems can be overcome using advanced antiviral delivery systems constructed using nanotechnology principles. These delivery systems consist of antivirals loaded into nanoparticles, which may be fabricated from either synthetic or natural materials. Nevertheless, there is increasing emphasis on the development of antiviral delivery systems from natural substances, such as lipids, phospholipids, surfactants, proteins, and polysaccharides, due to health and environmental issues. The composition, morphology, dimensions, and interfacial characteristics of nanoparticles can be manipulated to improve the handling, stability, and potency of antivirals. This article outlines the major classes of antivirals, summarizes the challenges currently limiting their efficacy, and highlights how nanoparticles can be used to overcome these challenges. Recent studies on the application of antiviral nanoparticle-based delivery systems are reviewed and future directions are described. Twit Text FOAVip Development of nanoparticle-delivery systems for antiviral agents: A review ????J Control Release http://www.kidney.de/pget.php?&tw=1&pmid=33450319 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33450319 #FOAvip English Wikipedia <ref>{{Cite pmid|33450319}}</ref> Development of nanoparticle-delivery systems for antiviral agents: A review #MMPMID33450319 Delshadi R; Bahrami A; McClements DJ; Moore MD; Williams L J Control Release 2021[Mar]; 331 (ä): 30-44 PMID33450319show ga The COVID-19 pandemic has resulted in unprecedented increases in sickness, death, economic disruption, and social disturbances globally. However, the virus (SARS-CoV-2) that caused this pandemic is only one of many viruses threatening public health. Consequently, it is important to have effective means of preventing viral transmission and reducing its devastating effects on human and animal health. Although many antivirals are already available, their efficacy is often limited because of factors such as poor solubility, low permeability, poor bioavailability, un-targeted release, adverse side effects, and antiviral resistance. Many of these problems can be overcome using advanced antiviral delivery systems constructed using nanotechnology principles. These delivery systems consist of antivirals loaded into nanoparticles, which may be fabricated from either synthetic or natural materials. Nevertheless, there is increasing emphasis on the development of antiviral delivery systems from natural substances, such as lipids, phospholipids, surfactants, proteins, and polysaccharides, due to health and environmental issues. The composition, morphology, dimensions, and interfacial characteristics of nanoparticles can be manipulated to improve the handling, stability, and potency of antivirals. This article outlines the major classes of antivirals, summarizes the challenges currently limiting their efficacy, and highlights how nanoparticles can be used to overcome these challenges. Recent studies on the application of antiviral nanoparticle-based delivery systems are reviewed and future directions are described. |*COVID-19 Drug Treatment[MESH] |*Drug Carriers[MESH] |*Nanoparticles[MESH] |Animals[MESH] |Antiviral Agents/*administration & dosage/chemistry[MESH] |COVID-19/virology[MESH] |Drug Compounding[MESH] |Humans[MESH] |Nanomedicine[MESH]Development of nanoparticle-delivery systems for antiviral agents: A r(epmc).pdf DeepDyve Pubget Overpricing