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10.1002/jmv.26797

http://scihub22266oqcxt.onion/10.1002/jmv.26797
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33448439!8014709!33448439
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suck abstract from ncbi


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pmid33448439      J+Med+Virol 2021 ; 93 (4): 2513-2522
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  • Association between red blood cell distribution width and mortality and severity among patients with COVID-19: A systematic review and meta-analysis #MMPMID33448439
  • Lee JJ; Montazerin SM; Jamil A; Jamil U; Marszalek J; Chuang ML; Chi G
  • J Med Virol 2021[Apr]; 93 (4): 2513-2522 PMID33448439show ga
  • Emerging evidence has underscored the potential usefulness of red blood cell distribution width (RDW) measurement in predicting the mortality and disease severity of COVID-19. This study aimed to assess the association of the plasma RDW levels with adverse prognosis in COVID-19 patients. A comprehensive literature search from inception to September 2020 was performed to harvest original studies reporting RDW on admission and clinical outcomes among patients hospitalized with COVID-19. RDW levels were compared between cases (patients who died or developed more severe symptoms) and controls (patients who survived or developed less severe symptoms). A total of 14,866 subjects from 10 studies were included in the meta-analysis. Higher levels of RDW were associated with adverse outcomes in COVID-19 patients (mean differences = 0.72; 95% CI = 0.47-0.97; I(2) = 89.51%). Deceased patients had higher levels of RDW compared to patients who survived (mean differences = 0.93; 95% CI = 0.63-1.23; I(2) = 85.58%). Severely ill COVID-19 patients showed higher levels of RDW, as opposed to patients classified to have milder symptoms (mean differences = 0.61; 95% CI = 0.28-0.94; I(2) = 82.18%). Elevated RDW levels were associated with adverse outcomes in COVID-19 patients. This finding warrants further research on whether RDW could be utilized as a simple and reliable biomarker for predicting COVID-19 severity and whether RDW is mechanistically linked with COVID-19 pathophysiology.
  • |Biomarkers/blood[MESH]
  • |COVID-19/*blood/*mortality/virology[MESH]
  • |Databases, Factual[MESH]
  • |Erythrocyte Indices[MESH]
  • |Erythrocytes/*pathology[MESH]
  • |Hospital Mortality[MESH]
  • |Humans[MESH]
  • |Prognosis[MESH]
  • |SARS-CoV-2/isolation & purification[MESH]


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