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10.1016/j.jvoice.2020.12.040 http://scihub22266oqcxt.onion/10.1016/j.jvoice.2020.12.040 33446439!ä!33446439 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Voice 2023 ; 37 (2): 302.e17-302.e20 Nephropedia Template TP {{tp|p=33446439|t=2023. Platelet-Rich Plasma for Vocal Fold Scar: A Preliminary Report of Concept |pdf=|usr=}}{{33446439}} gab.com Text Platelet-Rich Plasma for Vocal Fold Scar: A Preliminary Report of Concept JO: J Voice http://www.kidney.de/pget.php?&tw=1&pmid=33446439 #FOAvip INTRODUCTION: Vocal fold atrophy and scar can lead to loss of normal superficial lamina propria, negatively affecting the vibratory function of the vocal fold. These changes can lead to dysphonia, vocal fatigue, decreased volume, and altered pitch. Treatment options for these conditions are limited. Platelet-rich plasma (PRP) consists of platelets, growth factors, and cytokines derived from the patient's own blood and is believed to activate tissue regeneration. The purpose of this study was to review the technical aspects of collecting PRP and injecting it into the vocal fold injection - based on our initial experience with this procedure. CASE: A patient with vocal fold scar was identified and enrolled in an ongoing prospective clinical trial study of a series of 4 monthly subepithelial vocal fold PRP injections, which was temporarily halted due to the COVID-19 pandemic. Patient underwent a single injection of autologous PRP into the left vocal fold. There were no adverse events during the study period. Subjective improvement in voice was noted at 1 month after injection with subsequent return to baseline over the next 4 months. Videostroboscopy performed on postinjection day 1 and day 7 and demonstrated no concerning exam changes. Compared to the preinjection baseline, the patient-reported voice-handicap index-10 (VHI-10) and voice catastrophization index were similar at 4 months following injection (20 to 20 and 4 to 3, respectively). Independent perceptual analysis of voice showed improvement at 4 months postinjection, compared to baseline consensus auditory-perceptual evaluation of voice 60 to 44. CONCLUSIONS: This preliminary report was part of a prospective trial investigating the use of PRP to treat vocal fold atrophy and scar. This work highlights the technical considerations for injecting PRP into the vocal fold. Planned prospective enrollment in this study will help to validate the safety and efficacy of PRP injections. Twit Text FOAVip Platelet-Rich Plasma for Vocal Fold Scar: A Preliminary Report of Concept ????J Voice http://www.kidney.de/pget.php?&tw=1&pmid=33446439 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33446439 #FOAvip English Wikipedia <ref>{{Cite pmid|33446439}}</ref> Platelet-Rich Plasma for Vocal Fold Scar: A Preliminary Report of Concept #MMPMID33446439 Bhatt NK; Gao WZ; Timmons Sund L; Castro ME; O'Dell K; Johns MM 3rd J Voice 2023[Mar]; 37 (2): 302.e17-302.e20 PMID33446439show ga INTRODUCTION: Vocal fold atrophy and scar can lead to loss of normal superficial lamina propria, negatively affecting the vibratory function of the vocal fold. These changes can lead to dysphonia, vocal fatigue, decreased volume, and altered pitch. Treatment options for these conditions are limited. Platelet-rich plasma (PRP) consists of platelets, growth factors, and cytokines derived from the patient's own blood and is believed to activate tissue regeneration. The purpose of this study was to review the technical aspects of collecting PRP and injecting it into the vocal fold injection - based on our initial experience with this procedure. CASE: A patient with vocal fold scar was identified and enrolled in an ongoing prospective clinical trial study of a series of 4 monthly subepithelial vocal fold PRP injections, which was temporarily halted due to the COVID-19 pandemic. Patient underwent a single injection of autologous PRP into the left vocal fold. There were no adverse events during the study period. Subjective improvement in voice was noted at 1 month after injection with subsequent return to baseline over the next 4 months. Videostroboscopy performed on postinjection day 1 and day 7 and demonstrated no concerning exam changes. Compared to the preinjection baseline, the patient-reported voice-handicap index-10 (VHI-10) and voice catastrophization index were similar at 4 months following injection (20 to 20 and 4 to 3, respectively). Independent perceptual analysis of voice showed improvement at 4 months postinjection, compared to baseline consensus auditory-perceptual evaluation of voice 60 to 44. CONCLUSIONS: This preliminary report was part of a prospective trial investigating the use of PRP to treat vocal fold atrophy and scar. This work highlights the technical considerations for injecting PRP into the vocal fold. Planned prospective enrollment in this study will help to validate the safety and efficacy of PRP injections. |*COVID-19/pathology[MESH] |*Dysphonia[MESH] |*Laryngeal Diseases[MESH] |*Platelet-Rich Plasma[MESH] |Atrophy/pathology[MESH] |Cicatrix/pathology[MESH] |Humans[MESH] |Pandemics[MESH] |Prospective Studies[MESH] |Treatment Outcome[MESH]Platelet-Rich Plasma for Vocal Fold Scar: A Preliminary Report of Conc(epmc).pdf DeepDyve Pubget Overpricing